Frailty syndrome. What physicians and cardiologists need to know?


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Abstract

The review presents the data and evidences from recent clinical studies on the frailty syndrome - one of the most relevant clinical syndromes, though not studied well yet. The latest data on the prevalence of frailty and various factors contributing to its onset are reported. The presence of frailty is considered as an independent predictor of poor prognosis and high mortality rate. The role of frailty in the development of cardiovascular diseases, their progression and complicated course has been analyzed using the latest studies. In addition, the tendency towards higher incidence of frailty among the population of different countries and the poor prognosis of frail patients requires a series of clinical studies aimed at developing measures for primary and secondary prevention, as well as effective treatment strategies for frailty. The PubMed was used for a literature review.

About the authors

K E Krivoshapova

Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Disease”

Email: ya.kristi89@yandex.ru
к.м.н., н.с. лаб. патофизиологии мультифокального атеросклероза ФГБНУ «НИИ комплексных проблем сердечно-сосудистых заболеваний»; ORCID: 0000-0003-2384-5682 Kemerovo, Russia

E A Vegner

Federal State Budgetary Educational Institution of Higher Education “Kemerovo State Medical University”

аспирант каф. кардиологии и сердечно-сосудистой хирургии ФГБОУ ВО «Кемеровский государственный медицинский университет» Минздрава России, ORCID: 0000-0002-1175-0785 Kemerovo, Russia

O L Barbarash

Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Disease”; Federal State Budgetary Educational Institution of Higher Education “Kemerovo State Medical University”

д.м.н., проф., член-корр. РАН, директор ФГБНУ «НИИ комплексных проблем сердечно-сосудистых заболеваний»; зав. каф. кардиологии и сердечно-сосудистой хирургии ФГБОУ ВО «Кемеровский государственный медицинский университет» Минздрава России, ORCID: 0000-0002-4642-3610 Kemerovo, Russia

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