Antiviral therapy of chronic hepatitis C: 30 years success story


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Abstract

Exactly 30 years ago, hepatitis C virus was identified. Over the years, tremendous success has been achieved in the treatment of hepatitis C, which is currently considered to be an almost completely curable disease. The review presents the main stages in the development of hepatitis C antiviral therapy, the efficacy of various treatment regimens. The greatest progress in treatment was noted over the past 5 years when drugs with direct antiviral action appeared and began to be widely used, including in Russia, which ensure the elimination of the virus in 90-95% of cases.

About the authors

D T Abdurakhmanov

Tareev Clinic of Rheumatology Nephrology and Occupational Disease Sechenov First Moscow State Medical University

Email: abdjamal@mail.ru
д.м.н., проф. каф. внутренних, профессиональных болезней и ревматологии ФГАОУ ВО «Первый МГМУ им. И.М. Сеченова» Минздрава Россииu; ORCID: 0000-0002-3160-2771 Moscow, Russia

T P Rozina

Tareev Clinic of Rheumatology Nephrology and Occupational Disease Sechenov First Moscow State Medical University

к.м.н., доцент каф. внутренних, профессиональных болезней и ревматологии ФГАОУ ВО «Первый МГМУ им. И.М. Сеченова» Минздрава России Moscow, Russia

E N Nikulkina

Tareev Clinic of Rheumatology Nephrology and Occupational Disease Sechenov First Moscow State Medical University

ассистент каф. внутренних, профессиональных болезней и ревматологии ФГАОУ ВО «Первый МГМУ им. И.М. Сеченова» Минздрава России Moscow, Russia

E Z Burnevich

Tareev Clinic of Rheumatology Nephrology and Occupational Disease Sechenov First Moscow State Medical University

к.м.н., доцент каф. внутренних, профессиональных болезней и ревматологии ФГАОУ ВО «Первый МГМУ им. И.М. Сеченова» Минздрава России Moscow, Russia

E L Tanashuk

Tareev Clinic of Rheumatology Nephrology and Occupational Disease Sechenov First Moscow State Medical University

к.м.н., ассистент каф. внутренних, профессиональных болезней и ревматологии ФГАОУ ВО «Первый МГМУ им. И.М. Сеченова» Минздрава России Moscow, Russia

M V Severov

Tareev Clinic of Rheumatology Nephrology and Occupational Disease Sechenov First Moscow State Medical University

к.м.н., доцент каф. внутренних, профессиональных болезней и ревматологии ФГАОУ ВО «Первый МГМУ им. И.М. Сеченова» Минздрава России Moscow, Russia

A L Filatova

Tareev Clinic of Rheumatology Nephrology and Occupational Disease Sechenov First Moscow State Medical University

к.м.н., ассистент каф. внутренних, профессиональных болезней и ревматологии ФГАОУ ВО «Первый МГМУ им. И.М. Сеченова» Минздрава России Moscow, Russia

S Yu Milovanova

Tareev Clinic of Rheumatology Nephrology and Occupational Disease Sechenov First Moscow State Medical University

д.м.н., доцент каф. внутренних, профессиональных болезней и ревматологии ФГАОУ ВО «Первый МГМУ им. И.М. Сеченова» Минздрава России Moscow, Russia

V V Karpov

Tareev Clinic of Rheumatology Nephrology and Occupational Disease Sechenov First Moscow State Medical University

к.м.н., ассистент каф. внутренних, профессиональных болезней и ревматологии ФГАОУ ВО «Первый МГМУ им. И.М. Сеченова» Минздрава России Moscow, Russia

S V Moiseev

Tareev Clinic of Rheumatology Nephrology and Occupational Disease Sechenov First Moscow State Medical University

д.м.н., проф., зав. каф. внутренних, профессиональных болезней и ревматологии ФГАОУ ВО «Первый МГМУ им. И.М. Сеченова» Минздрава России Moscow, Russia

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