Exudative-constrictive tuberculous pericarditis in combination with arthritis in cardiologist practice: thoracoscopic biopsy as a diagnosis and treatment method


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Abstract

The goal is to present the possibilities of diagnosis verification, the features of the clinical picture of tuberculous pericarditis in the therapeutic clinic and the results of its treatment. Materials and methods. The paper presents clinical observation and a general analysis of 10 cases of tuberculous pericarditis in patients aged 31-79 (mean age 58.0 ± 15.1 years), 6 women and 4 men. Diagnostic puncture pericardium was performed on two patients, pleural puncture - on three Thoracoscopic biopsy of hilar lymph nodes and lung (n=1), pleura (n=1), supraclavicular lymph node biopsy (n=1). Dyskin test was carried out, as well as sputum examination, multispiral computed tomography, oncological search. Results. A 31-year-old patient with a massive effusion in the pericardial cavity, pleural lesion, arthritis of the left knee joint, whose results of the pericardial effusion and sputum were not diagnosed, tuberculosis was detected only with thoracoscopic biopsy of the lung and intrathoracic lymph nodes; the treatment via prednisolone and subtotal pericardectomy was performed. Among 10 patients with MSCT of the lung, changes were noted in general, but in only one case they were highly specific. Diaskin test is positive in 70%. In the study of punctata, bronchoalveolar flushing, Koch bacteria were not detected; at sputum in microscopy and biological sample BC was detected in two patients. The lymphocytic character of effusion in the pericardium / pleura is noted in 4 out of 5 cases. At a biopsy of lymphonoduses and a lung at 2 patients the picture of a granulomatous inflammation with a caseous necrosis. Pericarditis was predominantly large (from 2 cm and more) effusion, signs of constriction were noted in 50% of patients. Conclusion. Tuberculosis is one of the frequent causes of pericarditis in the Moscow therapeutic clinic. The most lymphocytic effusion with fibrin and the development of constriction. The negative results of all laboratory tests for tuberculosis do not exclude a diagnosis, It is necessary to use invasive morphological diagnostics, including thoracoscopic biopsy.

About the authors

O V Blagova

V.N. Vinogradov Faculty Therapeutic clinic of I.M. Sechenov First Moscow State Medical University (Sechenov University)

Email: blagovao@mail.ru
д.м.н., проф. каф. факультетской терапии №1 лечебного фак-та, https://orcid.org/0000-0002-5253-793X Moscow, Russia

I N Alijeva

V.N. Vinogradov Faculty Therapeutic clinic of I.M. Sechenov First Moscow State Medical University (Sechenov University)

врач-кардиолог отд-ния кардиологии факультетской терапевтической клиники им. В.Н.Виноградова, аспирант каф. факультетской терапии №1 лечебного фак-та Moscow, Russia

A V Nedostup

V.N. Vinogradov Faculty Therapeutic clinic of I.M. Sechenov First Moscow State Medical University (Sechenov University)

д.м.н., проф., проф. каф. факультетской терапии №1 лечебного фак-та, https://orcid.org/0000-0002-5426-3151 Moscow, Russia

A N Kaburova

V.N. Vinogradov Faculty Therapeutic clinic of I.M. Sechenov First Moscow State Medical University (Sechenov University)

клинический ординатор каф. факультетской терапии №1 лечебного фак-та Moscow, Russia

P V SenchihiN

V.N. Vinogradov Faculty Therapeutic clinic of I.M. Sechenov First Moscow State Medical University (Sechenov University)

к.м.н., зав. отд-нием терапии туберкулеза легких №2 НИИ фтизиопульмонологии, доцент каф. фтизиопульмонологии лечебного фак-та Moscow, Russia

V D Parshin

V.N. Vinogradov Faculty Therapeutic clinic of I.M. Sechenov First Moscow State Medical University (Sechenov University)

д.м.н., проф., член-корр. РАН, зав. отд-нием торакальной хирургии факультетской хирургической клиники Moscow, Russia

E A Kogan

V.N. Vinogradov Faculty Therapeutic clinic of I.M. Sechenov First Moscow State Medical University (Sechenov University)

д.м.н., проф., проф. каф. патологической анатомии лечебного фак-та Moscow, Russia

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