The first experience of non-interferon therapy of HCV infection in patients with Wilson-Konovalov’s disease


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Abstract

In the article we present three clinical observations demonstrating that HCV infection in patients with remission of Wilson disease causes an recrudescence of the disease, in one of the observations - decompensation of liver cirrhosis. In this study we first describe on the successful treatment of HCV infection with direct antiviral drugs in patients with Wilson disease. Establishment of all factors of liver damage and successful treatment (elimination of the virus, adequate lifelong medical treatment) allow to expect a favorable prognosis in patients with a combination of Wilson disease and HCV infection.

About the authors

T P Rozina

Faculty of Medicine, M.V. Lomonosov Moscow State University; I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation

Email: alrozin@ya.ru
к.м.н., доцент фак-та фундаментальной медицины МГУ им. М.В. Ломоносова, https://orcid.org/0000-0001-5943-6181 Moscow, Russia

T M Ignatova

Faculty of Medicine, M.V. Lomonosov Moscow State University; I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation

Email: tmignatova@gmail.com
д.м.н., проф. Moscow, Russia

S V Fastovets

Faculty of Medicine, M.V. Lomonosov Moscow State University; I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation

Email: s.v.fastovets@gmail.com
аспирант фак-та фундаментальной медицины МГУ им. М.В. Ломоносова Moscow, Russia

E E Starostina

Faculty of Medicine, M.V. Lomonosov Moscow State University

Email: starostinaee@gmail.com
к.м.н., Медицинский научно-образовательный центр МГУ им. М.В. Ломоносова Moscow, Russia

L M Samokhodskaia

Faculty of Medicine, M.V. Lomonosov Moscow State University

Email: slm@fbm.msu.ru
к.м.н., доцент, Медицинский научно-образовательный центр МГУ им. М.В. Ломоносова Moscow, Russia

T N Krasnova

Faculty of Medicine, M.V. Lomonosov Moscow State University; I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation

Email: krasnovamgu@yandex.ru
к.м.н., доцент фак-та фундаментальной медицины МГУ им. М.В. Ломоносова Moscow, Russia

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