Prevalence of external respiratory dysfunction in young people


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Abstract

Aim. To investigate the prevalence of impaired external respiration function (ERF) in young Novosibirsk dwellers. Subjects and methods. A cross-sectional population-based survey in one of the typical districts of Novosibirsk was conducted at the Research Institute of Internal and Preventive Medicine in 2013—2015. ERF was examined by spirometry in accordance with the guidelines. The best indicators of forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), and FEV1/FVC ratio were selected and three reproducible attempts were made to evaluate ERF. Spirometry was carried out in 787 respondents (358 males and 429 females) for the entire period. The results were interpreted according to the guidelines of the European Respiratory Society, the American Thoracic Society, and the Russian Respiratory Society. Results. The prevalence of a FEV1/FVC of <70% in the total sample was 10.3% (13.4% for men and 7.7% for women; p=0.009); a FEV1 of <80% was 13.9% (14.5% for men and 13.3% for women; p=0.617); a FVC of <80% was 7% (6.1% for men and 7.7% for women; p=0.397). The obstructive type of ventilation disorders (FEV1/FVC <70%, FVC ≥80%) was recorded in 9.4% of the people, the restrictive type (FVC <80%, FEV1/FVC ≥70%) in 6.1%, and the mixed one (FEV1/FVC <70%, FVC <80%) in 0.9%; normal values (FEV1/FVC ≥70% and FVC ≥80%) were seen in 83.6%. Conclusion. Spirometric screening of a young Novosibirsk population demonstrated the incidence of impaired ERF, which is comparable with Russian and foreign data.

About the authors

N A Kovalkova

Научно-исследовательский институт терапии и профилактической медицины

Новосибирск, Россия

N Yu Travnikova

Научно-исследовательский институт терапии и профилактической медицины

Новосибирск, Россия

Yu I Ragino

Научно-исследовательский институт терапии и профилактической медицины

Новосибирск, Россия

M I Voevoda

Научно-исследовательский институт терапии и профилактической медицины

Новосибирск, Россия

References

  1. Fox SJ. Human physiology. WCB and Oxford. England, 2012.
  2. Чучалин А.Г., Черняк А.В., Чикина С.Ю. Функциональная диагностика в пульмонологии. Практическое руководство. М.: Атмосфера; 2009.
  3. Lindberg A, Larsson LG, Rönmark E, Lundbäck B. Co-morbidity in mild-to-moderate COPD: comparison to normal and restrictive lung function. COPD. 2011;8:421-428. doi: 10.3109/15412555.2011.629858
  4. Guerra S, Sherrill DL, Venker C, Ceccato CM, Halonen M, Martinez FD. Morbidity and mortality associated with the restrictive spirometric pattern: a longitudinal study. Thorax. 2010;65:499-504. doi: 10.1136/thx.2009.126052
  5. Hankinson JL, Odencrantz JR, Fedan Hankinson KB. Spirometric Reference Values from a Sample of the General U.S. Population. Am J Respir Crit Care Med. 1999;159:179-187. doi: 10.1164/ajrccm.159.1.9712108
  6. Pellegrino R, Viegi G, Brusasco V, Crapo RO, Burgos F, Casaburi R, Coates A, C.P.M. van der Grinten, Gustafsson P, Hankinson J, Jensen R, Johnson DC, MacIntyre N, McKay R, Miller MR, Navajas D, Pedersen OF, Wanger J. Interpretative strategies for lung function tests. Eur Respir J. 2005;26:948-968. doi: 10.1183/09031936.05.00035205
  7. Чучалин А.Г., Айсанов З.Р., Чикина С.Ю., Черняк А.В., Калманова Е.Н. Федеральные клинические рекомендации по использованию метода спирометрии. Пульмонология, 2014;6:11-24.
  8. Логвиненко Н.И., Ковалькова Н.А., Воевода М.И., Малютина С.К. Распространенность бронхообструктивного синдрома в открытой популяции г. Новосибирска. Якутский медицинский журнал. 2013;44(4):22-24.
  9. Miller MR, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A, Crapo R, Enright P, C.P.M. van der Grinten, Gustafsson P, Jensen R, Johnson DC, MacIntyre N, McKay R, Navajas D, Pedersen OF, Pellegrino R, Viegi G, Wanger J. Standardisation of spirometry. Eur Respir J. 2005;26:319-338. doi: 10.1183/09031936.05.00034805
  10. Княжеская Н.П., Новиков Ю.К. Комбинированные быстродействующие бронхолитики в лечении обструктивных заболеваний легких. Consilium medicum. 2012;14(3):21-30.
  11. Probst-Hensch NM, Curjuric I, Pierre-Olivier B, Ckermann-Liebrich U, Bettschart RW, Brandli O, Brutsche M, Burdet L, Gerbase MW, Knöpfli B, Künzli N, Pons MG, Schindler C, Tschopp JM, Rochat T, Russi EW: Longitudinal change of prebronchodilator spirometric obstruction and health outcomes: results from the SAPALDIA cohort. Thorax. 2010,65(2):150-156. doi: 10.1136/thx.2009.115063
  12. de Marco R, Accordini S, Marcon A, Cerveri I, Antó JM, Gislason T, Heinrich J, Janson C, Jarvis D, Künzli N, Leynaert B, Sunyer J, Svanes C, Wjst M, Burney P. Risk factors for chronic obstructive pulmonary disease in a European cohort of young adults. Am J Respir Crit Care Med . 2011;(7):891-897. doi: 10.1164/rccm.201007-1125OC
  13. Vaz Fragoso СA, Concato J, McAvay G, Van Ness PH, Rochester CL, Yaggi HK, Gill TM. The Ratio of FEV1 to FVC as a Basis for Establishing Chronic Obstructive Pulmonary Disease.Am J Respir Crit Care Med. 2010;181(5):446-451. doi: 10.1164/rccm.200909-1366OC
  14. Al-Hazmi M, Wooldrage K, Anthonisen NR, Becklake MR, Bowie D, Chan-Yeung M, Dimich-Ward H, Ernst P,, Manfreda J, Sears MR, Siersted HC, Sweet L. Airflow obstruction in young adults in Canada. Can Respir J. 2007;14(4):221-227.
  15. Smith M, Li L, Augustyn M, Kurmi O, Chen J, Collins R, Guo Y, Han Y, Qin J, Xu G, Wang J, Bian Z, Zhou G, Peto R, Chen Z. Prevalence and correlates of airflow obstruction in 317 000 never-smokers in China. Eur Respir J. 2014;44(1):66-77. doi: 10.1183/09031936.00152413
  16. Shin C, In KH, Shim JJ, Yoo SH, Kang KH, Hong M, Choi K. Prevalence and correlates of airway obstruction in a community-based sample of adults. Chest. 2003;123(6):1924-1931. doi: 10.1378/chest.123.6.1924
  17. Gibson GJ, Loddenkemper R, Lundbäck B, Sibille Y. Respiratory health and disease in Europe: the new European Lung White Book. European Respiratory Society Journals Ltd. 2003. doi: 10.1183/09031936.00105513
  18. Денисова Д.В., Ковалькова Н.А., Каштанова Е.В., Полонская Я.В., Щербакова Л.В. Курение и его ассоциации с социально-экономическими и кардиометаболическими факторами риска в популяции 25—45 лет г. Новосибирска. Проблема женского курения (2013—2014 гг.) Атеросклероз. 2014;3:61-67.
  19. Chen YS, Li XQ, Li HR, Yu XL, Lu FF, Huang LP, Miao Y, Wang GQ, Lin X, Lian SQ, Lin YH, Zhang XE, Liu T, Wu YL. Spirometric prediction equations and the relationship between metabolic syndrome and spirometric parameters from an island in Fujian, China. Clin Respir J. 2015;ISSN 1752-6981. doi: 10.1111/crj.12381
  20. Soriano JB, Miravitlles M, García-Río F, Muñoz L, Sánchez G, Sobradillo V, Durán E, Guerrero D, Ancochea J. Spirometrically-defined restrictive ventilatory defect: population variability and individual determinants. Prim Care Respir J. 2012;21(2):187-193. doi: 10.4104/pcrj.2012.00027
  21. Ford ES, Wheaton AG, Mannino DM, Presley-Cantrell L, Li C, Croft JB. Elevated cardiovascular risk among adults with obstructive and restrictive airway functioning in the United States: a cross-sectional study of the National Health and Nutrition Examination Survey from 2007—2010. Respir Res. 2012;13;13:115. doi: 10.1186/1465-9921-13-115
  22. MacIntyre NR, Selecky PA. Is there a role for screening spirometry? Respir Care. 2010;55:35-42.
  23. Mannino DM, Doherty DE, Sonia Buist A. Global Initiative on Obstructive Lung Disease (GOLD) classification of lung disease and mortality: findings from the Atherosclerosis Risk in Communities (ARIC) study. Respir Med. 2006;100:115-122. doi: 10.1016/j.rmed.2005.03.035
  24. Lee JY, Hwang YI, Park YB, Park JY, Kim KU, Oh YM, Yoon HK, Yoon HI, Sheen SS, Lee SY, Lee CH, Lee HB, Lim SC, Jung SS, Oh K, Kim Y, Chun C, Yoo KH. Prevalence of Spirometrically-defined Restrictive Ventilatory Defect in Korea: The Fourth-2, 3, and Fifth Korean National Health and Nutrition Examination Survey, 2008-2012. J Korean Med Sci. 2015;30(6):725-732. doi: 10.3346/jkms.2015.30.6.725
  25. Hebert JR, Pednekar MS, Gupta PC. Forced expiratory volume predicts all-cause and cancer mortality in Mumbai, India: results from a population-based cohort study. Int J Epidemiol. 2010; 39 (6):1619-1627. doi: 10.1093/ije/dyq157
  26. Menezes AM, Pérez-Padilla R, Wehrmeister FC, Lopez-Varela MV, Muiño A, Valdivia G, Lisboa C, Jardim JR, de Oca MM, Talamo C,Bielemann R, Gazzotti M, Laurenti R, Celli B, Victora CG. FEV1 is а better predictor of mortality than FVC: the PLATINO cohort study. PLoS One. 2014;9(10):e109732. doi: 10.1371/journal.pone.0109732
  27. Masuko H, Sakamoto T, Kaneko Y, Lower FEV1 in non-COPD, nonasthmatic subjects: association with smoking, annual decline in FEV1, total IgE levels, and TSLP genotypes. Int J Chron Obstruct Pulmon Dis. 2011;6:181-189 doi: 10.2147/COPD.S16383
  28. Окончательные итоги дня спирометрии и легочного здоровья в России. Результаты дня спирометрии 2010. Российское респираторное общество. Cсылка активна на 21.09.2015. Доступно по: http://www.pulmonology.ru/about/projects/spirometry_day/Results_tmp.php
  29. Buffels J, Degryse J, Heyrman J, Decramer M. Office spirometry significantly improves early detection of COPD in general practice: the DIDASCO Study (Randomized Controlled Trial). Chest. 2004;125(4):1394-1399. doi: 10.1378/chest.125.4.1394

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