Email this article Cholagenic diarrhea is a type of postcholescystectomy syndrome
- Authors: Krums LM1, Parfenov AI1, Gubina AV1, Sil'vestrova SI.1, Smirnova AV1
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Affiliations:
- ЦНИИ гастроэнтерологии Департамента здравоохранения Москвы
- Issue: Vol 85, No 2 (2013)
- Pages: 32-35
- Section: Editorial article
- URL: https://journals.rcsi.science/0040-3660/article/view/31199
- ID: 31199
Cite item
Abstract
AIM: To study the role of biliary acids (BAs) in the pathogenesis of chronic diarrhea (CD) in patients undergoing cholecystectomy (CE)/MATERIAL AND METHODS: Twenty-five patients with post-CE diarrhea were examined. A comparison group consisted of 11 patients with diarrhea-predominant irritable bowel syndrome (IBS). The results of an examination of 15 healthy individuals were taken as normal values. Daily fecal BAs were determined by an enzyme spectrophotometric technique/RESULTS: In the patients after CE, daily fecal BA losses were found to be thrice as large as that in the healthy individuals. In the comparison group of patients with IBS, fecal bile excretion was not greater than the normal values. Stool normalization with a simultaneous decrease in fecal BA losses was seen in 92% of the post-CE patients receiving a course of therapy with adsorbents and astringents/CONCLUSION: Post-CE CD is a type of postcholescystectomy syndrome.
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##article.viewOnOriginalSite##About the authors
L M Krums
ЦНИИ гастроэнтерологии Департамента здравоохранения Москвы
Email: gastroenter@rambler.ru
111123 Москва, ш. Энтузиастов, д. 86
A I Parfenov
ЦНИИ гастроэнтерологии Департамента здравоохранения Москвы
A V Gubina
ЦНИИ гастроэнтерологии Департамента здравоохранения Москвы
S Iu Sil'vestrova
ЦНИИ гастроэнтерологии Департамента здравоохранения Москвы
A V Smirnova
ЦНИИ гастроэнтерологии Департамента здравоохранения Москвы
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