电邮这篇文章 Efficiency of use of autologous activated serum in coxarthrosis
- 作者: Noskov SM1, Shirokova LI.1, Snigireva AV1, Parulia OM1, Dybin SD2
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隶属关系:
- ГБОУ ВПО "Ярославская государственная медицинская академия" Минздравсоцразвития России
- Муниципальное клиническое учреждение здравоохранения (МКУЗ) "Медсанчасть Ярославского завода дизельной аппаратуры"
- 期: 卷 84, 编号 8 (2012)
- 页面: 33-36
- 栏目: Editorial
- URL: https://journals.rcsi.science/0040-3660/article/view/31068
- ID: 31068
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Aim. To evaluate the clinical efficiency of using autologous conditioned (activated) serum (ACS) versus hyaluronic acid (HA) in coxarthrosis (CA). Subjects and methods. Two groups of patients (n=54) who were matched for age, sex, and disease duration and had a valid diagnosis of CA were examined. During 3 weeks, Groups 1 and 2 patients received intra-articular therapy with ACS or synocrome forte (Croma Pharma, Sоtex), respectively, for 3 weeks. A 12-month follow-up evaluated the magnitude of pain, by using the visual analog scale (VAS, mm), the functional index WOMAC and general health, by applying the EQ-VAS scale. Results. The only benefit of HA was found to be more functional improvement as detected by the WOMAC index (-21.8%; t=2.56) at an early (1-month) follow-up. After 3 months, the patients in the ACS group were recorded to have the maximum VAS pain intensity reduction that was 76.5% greater than that (t=4.31) in the HA group. The clearest advantages of ACS therapy were traced 6 months after treatment. Conclusion. The use of ACS may be a real alternative to that of HA derivatives in achieving good clinical outcomes in patients with CA. After ACS administration, there was a long-term preservation of achieved positive results.
作者简介
S Noskov
ГБОУ ВПО "Ярославская государственная медицинская академия" Минздравсоцразвития России
L Shirokova
ГБОУ ВПО "Ярославская государственная медицинская академия" Минздравсоцразвития России
Email: Larshir@gmail.com
A Snigireva
ГБОУ ВПО "Ярославская государственная медицинская академия" Минздравсоцразвития России
O Parulia
ГБОУ ВПО "Ярославская государственная медицинская академия" Минздравсоцразвития России
S Dybin
Муниципальное клиническое учреждение здравоохранения (МКУЗ) "Медсанчасть Ярославского завода дизельной аппаратуры"
参考
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