Email this article Efficiency of use of autologous activated serum in coxarthrosis
- Authors: Noskov SM1, Shirokova LI.1, Snigireva AV1, Parulia OM1, Dybin SD2
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Affiliations:
- ГБОУ ВПО "Ярославская государственная медицинская академия" Минздравсоцразвития России
- Муниципальное клиническое учреждение здравоохранения (МКУЗ) "Медсанчасть Ярославского завода дизельной аппаратуры"
- Issue: Vol 84, No 8 (2012)
- Pages: 33-36
- Section: Editorial
- URL: https://journals.rcsi.science/0040-3660/article/view/31068
- ID: 31068
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Abstract
Aim. To evaluate the clinical efficiency of using autologous conditioned (activated) serum (ACS) versus hyaluronic acid (HA) in coxarthrosis (CA). Subjects and methods. Two groups of patients (n=54) who were matched for age, sex, and disease duration and had a valid diagnosis of CA were examined. During 3 weeks, Groups 1 and 2 patients received intra-articular therapy with ACS or synocrome forte (Croma Pharma, Sоtex), respectively, for 3 weeks. A 12-month follow-up evaluated the magnitude of pain, by using the visual analog scale (VAS, mm), the functional index WOMAC and general health, by applying the EQ-VAS scale. Results. The only benefit of HA was found to be more functional improvement as detected by the WOMAC index (-21.8%; t=2.56) at an early (1-month) follow-up. After 3 months, the patients in the ACS group were recorded to have the maximum VAS pain intensity reduction that was 76.5% greater than that (t=4.31) in the HA group. The clearest advantages of ACS therapy were traced 6 months after treatment. Conclusion. The use of ACS may be a real alternative to that of HA derivatives in achieving good clinical outcomes in patients with CA. After ACS administration, there was a long-term preservation of achieved positive results.
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##article.viewOnOriginalSite##About the authors
S M Noskov
ГБОУ ВПО "Ярославская государственная медицинская академия" Минздравсоцразвития России
L Iu Shirokova
ГБОУ ВПО "Ярославская государственная медицинская академия" Минздравсоцразвития России
Email: Larshir@gmail.com
A V Snigireva
ГБОУ ВПО "Ярославская государственная медицинская академия" Минздравсоцразвития России
O M Parulia
ГБОУ ВПО "Ярославская государственная медицинская академия" Минздравсоцразвития России
S D Dybin
Муниципальное клиническое учреждение здравоохранения (МКУЗ) "Медсанчасть Ярославского завода дизельной аппаратуры"
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