Effect of bortezomib on the efficiency of hematopoietic stem cell mobilization in patients with multiple myeloma
- Authors: Pokrovskaia OS1, Mendeleeva LP1, Urnova ES1, Gaponova TV1, Gal'tseva IV1, Kuz'mina LA1, Akhundova FM1, Kalinin NN1, Gretsov EM1, Parovichnikova EN1, Savchenko VG1
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Affiliations:
- ФГБУ "Гематологический научный центр" Минздравсоцразвития России, Москва
- Issue: Vol 84, No 7 (2012)
- Pages: 35-41
- Section: Editorial
- URL: https://journals.rcsi.science/0040-3660/article/view/31058
- ID: 31058
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##article.viewOnOriginalSite##About the authors
O S Pokrovskaia
ФГБУ "Гематологический научный центр" Минздравсоцразвития России, Москва
Email: pokrovskaya.o.s@yandex.ru
L P Mendeleeva
Email: mlp@blood.ru
E S Urnova
Email: eurnova@mail.ru
T V Gaponova
Email: gaponova.tatj@yandex.ru
I V Gal'tseva
Email: irag@blood.ru
L A Kuz'mina
Email: kuzlara@rambler.ru
F M Akhundova
Email: rf_fina@hotmail.com
N N Kalinin
Email: kalininn@blood.ru
E M Gretsov
E N Parovichnikova
Email: elenap@blood.ru
V G Savchenko
Email: svg@blood.ru
References
- Child J.A., Morgan G.J., Davies F.E. et al. High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma. N Engl J Med 2003; 348: 1875-1883.
- Attal M., Harousseau J.L., Stoppa A.M. et al. A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma. Intergroupe Francais du Myelome. N Engl J Med 1996; 335: 91-97.
- O'Shea D., Giles C., Terpos E. et al. Predictive factors for survival in myeloma patients who undergo autologous stem cell transplantation: a single-centre experience in 211 patients. Bone Marrow Transplant 2006; 37: 731-737.
- Dingli D., Pacheco J.M., Dispenzieri A. et al. Serum M-spike and transplant outcome in patients with multiple myeloma. Cancer Sci 2007; 98: 1035-1040.
- Barlogie B., Kyle R.A., Anderson K.C. et al. Standard chemotherapy compared with high-dose chemoradiotherapy for multiple myeloma: final results of phase III US Intergroup Trial S9321. J Clin Oncol 2006; 24: 929-936.
- Blade J., Rosinol L., Sureda A. et al. High-dose therapy intensification compared with continued standard chemotherapy in multiple myeloma patients responding to the initial chemotherapy: long-term results from a prospective randomized trial from the Spanish cooperative group PETHEMA. Blood 2005; 106: 3755-3759.
- Fermand J.P., Katsahian S., Divine M. et al. Highdose therapy and autologous blood stem-cell transplantation compared with conventional treatment in myeloma patients aged 55 to 65 years: long-term results of a randomized control trial from the Group Myelome-Autogreffe. J Clin Oncol 2005; 23: 9227-9233.
- Fermand J.P., Ravaud P., Chevret S. et al. Highdose therapy and autologous peripheral blood stem cell transplantation in multiple myeloma: up-front or rescue treatment? results of a multicenter sequential randomized clinical trial. Blood 1998; 92: 3131-3136.
- Palumbo A., Bringhen S., Petrucci M.T. et al. Intermediate-dose melphalan improves survival of myeloma patients aged 50 to 70: results of a randomized controlled trial. Blood 2004; 104: 3052-3057.
- Kumar S.K., Rajkumar S.V., Dispenzieri A. et al. Improved survival in multiple myeloma and the impact of novel therapies. Blood 2008; 111: 2516-2520.
- Baldomero H., Gratwohl M., Gratwohl A. et al. The EBMT activity survey 2009: trends over the past 5 years. Bone Marrow Transplant 2011; 46 (4): 485-501.
- Менделеева Л.П., Митиш Н.Е., Клясова Г.А. и др. Инфекционные осложнения после трансплантации аутологичных гемопоэтических клеток при гемобластозах. Тер арх 2005; 7: 33-39.
- Менделеева Л.П., Савченко В.Г., Павлова О.А. и др. Мобилизация гранулоцитарным колониестимулирующим фактором аутологичных гемопоэтических клеток крови у больных лимфомами и раком молочной железы. Пробл гематол 1999; 4: 5-12.
- Siena S., Schiavo R., Pedrazzoli P. et al. Therapeutic relevance of CD34 cell dose in blood cell transplantation for cancer therapy. J Clin Oncol 2000; 18: 1360-1377.
- Sola C., Maroto P., Salazar R. et аl. Bone marrow transplantation: prognostic factors of peripheral blood stem cell mobilization with cyclophospamide and filgrastim (r-metHuG-CSF): the CD34+cell dose positively affects the time of hematopoietic recovery and supportive requirements after high-dose chemotherapy. Hematology 1999; 4: 195-209.
- Gordan L.N., Sugrue M.W., Lynch J.W. et al. Poor mobilization of peripheral blood stem cells is a risk factor for worse outcome in lymphoma patients undergoing autologous stem cell transplantation. Leuk Lymphoma 2003; 44: 815-820.
- Toor A.A., Ayers J., Strupeck J. et al. Favourable results with a single autologous stem cell transplant following conditioning with busulphan and cyclophosphamide in patients with multiple myeloma. Br J Haematol 2004; 124: 769-776.
- Cottler-Fox M.H., Lapidot T., Petit I. et al. Stem cell mobilization. In 45-th Annual Meeting of American Society of Hematology. Educ. Program Book: San-Diego; 2003; Hematology 2003 (1): 419-437.
- Kuittinen T., Nousiainen T., Halonen P. et al. Prediction of mobilization failure in patients with non-Hodgkin's lymphoma. Bone Marrow Transplant 2004; 33: 907-912.
- Покровская О.С., Менделеева Л.П., Урнова Е.С. и др. Оптимизация режимов мобилизации гемопоэтических стволовых клеток у больных с множественной миеломой. Тер арх 2011; 7: 50-57.
- Attal M., Harousseau J.L., Facon T. et al. Single versus double autologous stem cell transplantation for multiple myeloma. N Engl J Med 2003; 349: 2495-2502.
- Fermand J.P., Ravaud P., Katsahian S. et al. High dose therapy (HDT) and autologous blood stem cell (ABSC) transplantation versus conventional treatment in multiple myeloma (MM): results of a randomized trial in 190 patients 55 to 65 years of age. Blood 1999; 94: Suppl 1: 396.
- Tribalto M., Amadori S., Cudillo L. et al. Autologous peripheral blood stem cell transplantation as first line treatment of multiple myeloma: an Italian multicenter study. Haematologica 2000; 85: 52-58.
- Kyle R.A., Rajkumar V. Multiple myeloma. N Engl J Med 2004; 351: 1860-1873.
- Richardson P.G., Barlogie B., Berenson J. et al. A phase 2 study of bortezomib in relapsed, refractory myeloma. N Engl J Med 2003; 348: 2609-2617.
- Jagannath S., Barlogie B., Berenson J. et al. A phase 2 study of two doses of bortezomib in relapsed or refractory myeloma. Br J Haematol 2004;127: 165-172.
- Fitzgerald M., Fraser C., Webb I. et al. Normal hematopoietic stem cell function in mice following treatment with bortezomib. Biol Blood Marrow Transpl 2003; 9: 193.
- Lonial S., Waller E.K., Richardson P.G. et al. Risk factors and kinetics of thrombocytopenia associated with bortezomib for relapsed, refractory multiple myeloma. Blood 2005; 106 (12): 3777-3784.
- Harousseau J.L., Mathiot C., Attal M. et al. Bortezomib/dexamethasone versus VAD as induction prior to autologous stem cell transplantion (ASCT) in previously untreated multiple myeloma (MM): updated data from IFM 2005/01 trial [abstract]. J Clin Oncol 2008; 26: 8505.
- Sonneveld P., van der Holt B., Schmidt-Wolf I.G.H. et al. First analysis of HOVON-65/GMMG-HD4 randomized phase iii trial comparing bortezomib, adriamycine, dexamethasone (PAD) vs VAD as induction treatment prior to high dose melphalan (HDM) in patients with newly diagnosed multiple myeloma (MM) [abstract]. Blood 2008; 112: 653.
- Oakervee H., Popat R., Cavenagh J.D. Use of bortezomib as induction therapy prior to stem cell transplantation in frontline treatment of multiple myeloma: impact on stem cell harvesting and engraftment. Leuk Lymphoma 2007; 48 (10): 1910-1921.
- Pokrovskaya O., Mendeleeva L., Alexeeva I. et al. Treatment of multiple myeloma with autologous stem cell transplantation: a long-term observation. Bone Marrow Transplant 2011; 46: Suppl 1: P906 [abstract].
- Поспелова Т.И, Скворцова Н.В., Нечунаева И.Н. Результаты лечения множественной миеломы препаратом бортезомиб. Онкогематол 2009; 2: 35-41.
- Бессмельцев С.С., Стельмашенко Л.В., Подольцева Э.И. и др. Бортезомиб (велкейд) в комбинации с дексаметазоном при рецидиве и рефрактерных формах множественной миеломы. Онкогематол 2007; 4: 61-66.
- Вотякова О.М. Современная терапия множественной миеломы. Бюл сибирской мед 2008; Приложение 3: 33-41.
- Лучинин А.С., Загоскина Т.П. Эффективность применения комбинации бортезомиба, мелфалана и преднизолона при множественной миеломе. Гематол и трансфузиол 2009; 4: 9-13.
- The International Myeloma Working Group. Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders: a report of the International Myeloma Working Group. Br J Haematol 2003; 121 (5): 749-757.
- Durie B.G.M., Harousseau J.L., Miguel J.S. et al. International uniform response criteria for multiple myeloma. Leukemia 2006; 20 (9): 1467-1473.
- Harousseau J.L., Attal M., Leleu X. et al. Bortezomib plus dexamethasone as induction treatment prior to autologous stem cell transplantation in patients with newly diagnosed multiple myeloma: results of an IFM phase II study. Haematologica 2006; 91: 1498-1505.
- Harousseau J.L., Marit G., Caillot D. et al. VELCADE/dexamethasone (Vel/Dex) versus VAD as induction treatment prior to autologous stem cell transplantation (ASCT) in newly diagnosed multiple myeloma (MM): an interim analysis of the IFM 2005-01 randomized multicenter phase III trial. Blood 2006; 108: 21a.
- Barlogie B., Anaissie E., van Rhee F. et al. Incorporating bortezomib into upfront treatment for multiple myeloma: early results of total therapy 3. Br J Haematol 2007; 138: 176-185.
- Oakervee H., Popat R., Curry N. et al. PAD combination therapy (PS-341/bortezomib, doxorubicin and dexamethasone) for previously untreated patients with multiple myeloma. Br J Haematol 2005; 129: 755-762.
- Van de Velde H.J.K., Liu X., Chen G. et al. Complete response correlates with long-term survival and progression-free survival in high-dose therapy in multiple myeloma. Haematologica 2007; 92: 1399-1406.
- Lahuerta J.J., Mateos M.V., Martinez-Lopez J. et al. Influence of pre- and post-transplantation responses on outcome of patients with multiple myeloma: sequential improvement of response and achievement of complete response are associated with longer survival. J Clin Oncol 2008; 26: 5775-5782.
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