Email this article Role of obesity in the development of osteoarthrosis and concomitant diseases
- Authors: Denisov L.N.1, Nasonova V.A.1, Koreshkov G.G.1, Kashevarova N.G.1, Denisov LN1, Nasonova VA1, Koreshkov GG1, Kashevarova NG1
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Affiliations:
- Учреждение Российской академии медицинских наук Научно-исследовательский институт ревматологии
- Issue: Vol 82, No 10 (2010)
- Pages: 34-37
- Section: Editorial
- URL: https://journals.rcsi.science/0040-3660/article/view/30674
- ID: 30674
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Abstract
Subjects and methods: The study included 298 patients with manifest knee and hip osteoarthrosis in whom the body mass index (BMI) and waist and hip circumferences were measured calculating the waist-hip index. The association of these indices with the severity of OA and the development of concomitant states was analyzed.
Results. Both women and men were found to have overweight and first-second-degree obesity at equal ratios - 61.6 and 59%, respectively. There was an evident rise in the prevalence of cardiovascular diseases (arterial hypertension, coronary heart disease) and diabetes mellitus with a higher BMI. Stages II-III gonarthrosis was predominant (97.1%) in the obesity group (BMI 30.0-35.0 or greater). With a BMI of > 40, X-ray stages III-IV OA were revealed in 83.3% of the patients.
Conclusion. Our findings support the important role of obesity as a risk factor in the development of OA. Fat metabolic disturbances also make a considerable contribution in the development of concomitant states and in the progression of OA of both knee and hand joints.
Keywords
About the authors
Lev Nikolaevich Denisov
Учреждение Российской академии медицинских наук Научно-исследовательский институт ревматологиид-р мед. наук, зав. лаб. клинических исследований и международных связей; Учреждение Российской академии медицинских наук Научно-исследовательский институт ревматологии
Valentina Aleksandrovna Nasonova
Учреждение Российской академии медицинских наук Научно-исследовательский институт ревматологииакад. РАМН, главный науч. сотр., лаб. клинических исследований и международных связей; Учреждение Российской академии медицинских наук Научно-исследовательский институт ревматологии
Gavrila Georgievich Koreshkov
Учреждение Российской академии медицинских наук Научно-исследовательский институт ревматологиист. науч. сотр; Учреждение Российской академии медицинских наук Научно-исследовательский институт ревматологии
Natal'ya Gavrilovna Kashevarova
Учреждение Российской академии медицинских наук Научно-исследовательский институт ревматологииврач-ревматолог, отд-ние эпидемиологии и генетики; Учреждение Российской академии медицинских наук Научно-исследовательский институт ревматологии
L N Denisov
V A Nasonova
G G Koreshkov
N G Kashevarova
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