Norovirus infection in general hospitals for adults
- Authors: Sagalova OI, Bryzgalova IV, Podkolzin AT, Maleev VV, Sagalova OI, Bryzgalova IV, Podkolzin AT, Maleev VV
- Issue: Vol 81, No 4 (2009)
- Pages: 60-63
- Section: Editorial
- URL: https://journals.rcsi.science/0040-3660/article/view/30322
- ID: 30322
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Abstract
Material and methods. Routine diagnostic methods and diagnostic tests on the base of polymerase chain reaction (PCR) were used for identification of group A rotaviruses, noroviruses, astroviruses, adenoviruses, salmonella, thermophilic campilobacteria, shigella, enteroinvasive echerichia (EIEC) in 70 adult patients with AII transferred from general hospital to infection hospital in 2003-2007. A part of the strains was typed with primers specific for genetic cluster G2/4.
Results. Routine methods failed to identify causes of hospital infection. PCR detected AII etiology in 77.8% patients. Norovirus of the second genotype (G2) was identified as monoinfection in 87.8% verified cases, in association with other agents - in 12.2%. Typed noroviruses belonged to cluster G2/4. Nosocomial norovirus infection was characterized by winter-spring occurrence and a moderate course.
Conclusion. An essential role of noroviruses in hospital AII outbreaks in elderly patients in winter-spring is shown.
Keywords
About the authors
O I Sagalova
I V Bryzgalova
A T Podkolzin
V V Maleev
O I Sagalova
I V Bryzgalova
A T Podkolzin
V V Maleev
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