Email this article Phenotypes of patients with chronic obstructive pulmonary disease
- Authors: Aver'yanov AV, Chuchalin AG, Polivanova AE, Polivanov GE, Chernyak AV, Neklyudova GV, Naumenko Z.K, Averianov AV, Chuchalin AG, Polivanova AE, Polivanov GE, Chernyak AV, Neklyudova GV, Naumenko Z.K
- Issue: Vol 81, No 3 (2009)
- Pages: 9-14
- Section: Editorial
- URL: https://journals.rcsi.science/0040-3660/article/view/30272
- ID: 30272
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Abstract
Material and methods. Basing on the results of high performance computed tomography, 64 COPD patients aged 46-75 years (FEV1 51 ± 24%) were divided into two groups: 53 patients with emphysematous phenotype (group 1) and 11 patients with bronchytic phenotype (group 2). The groups were compared by constitutional, clinical, functional and roentgenological parameters.
Results. Group 1 patients had significantly less body mass index, more severe edema by Borg's scale, low FEV1, FEV1/FLC, diffuse lung capacity and lung tissue density compared to group 2. Bronchoectases occurred more frequently in group 1 (33 and 9%, respectively).
Conclusion. Heterogenous COPD phenotypes differ not only at the stage of chronic respiratory insufficiency but also at all stages of the disease.
About the authors
A V Aver'yanov
A G Chuchalin
A E Polivanova
G E Polivanov
A V Chernyak
G V Neklyudova
Zh K Naumenko
A V Averianov
A G Chuchalin
A E Polivanova
G E Polivanov
A V Chernyak
G V Neklyudova
Zh K Naumenko
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