Behcet's disease and joint affection


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Abstract

Aim. To study joint pathology in patients with Behcet's disease (BD). Material and methods. The trial enrolled 183 BD patients (128 males, 54 females, mean age 32,0 ± 9.8 years, age at BD onset 22.3 ± 9.9 years, mean duration of the disease 9.5 ± 8.9 years. Results. Joint pathology occurred in 74.8% patients, in 10.9% patients the disease onset was associated with arthritis and arthralgia. 3 patients had aceptic necrosis of the head of the femur and knee joint, 3 patients - bone marrow infarction. Knee joints were affected more frequently than others (up to 40%) followed by ankle, elbow and radiocarpal and other joints. In BD duration about 10 years, none of the examinees had stage III of sacroiliitis, stage II was diagnosed only in 4 patients, stage I (suspicion) - in 9. Significant sacroillitis was not registered, bilateral sacroillitis occurred only in 9 patients. HLA B5 was detected in 61% patients while HLA B27 - only in 9.7%. Conclusion. The articular syndrome was seen in 3/4 of BD patients. Arthritis runs a recurrent course. Erosive arthritis, sacroillitis and combination of the latter with HLA B27 are rare.

About the authors

Z S Alekberova

ГУ Институт ревматологии РАМН, Москва

A V Elonakov

ГУ Институт ревматологии РАМН, Москва

R G Goloeva

ГУ Институт ревматологии РАМН, Москва

A V Smirnov

ГУ Институт ревматологии РАМН, Москва

I A Guseva

ГУ Институт ревматологии РАМН, Москва

E L Nasonov

ГУ Институт ревматологии РАМН, Москва

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