Prevention and treatment of COVID-19 based on post-genomic pharmacological analysis: Systematic computer analysis of 290,000 scientific articles on COVID-19
- Authors: Torshin I.Y.1, Gromova O.A.1, Chuchalin A.G.2
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Affiliations:
- Federal Research Center “Computer Science and Control” of the Russian Academy of Sciences
- Pirogov Russian National Research Medical University
- Issue: Vol 96, No 3 (2024)
- Pages: 205-211
- Section: Editorial
- URL: https://journals.rcsi.science/0040-3660/article/view/255124
- DOI: https://doi.org/10.26442/00403660.2024.03.202635
- ID: 255124
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Abstract
The COVID-19 pandemic has highlighted pressing challenges in biomedical research methodology. It has become obvious that the rapid and effective development of treatments for “new” viral infections is impossible without the coordination of interdisciplinary research and in-depth analysis of data obtained within the framework of the post-genomic paradigm. Presents the results of a systematic computer analysis of 290,000 scientific articles on COVID-19, with an emphasis on the results of post-genomic studies of SARS-CoV-2. The futility of the overly simplified approach, which considers only one “most important receptor protein”, only one “key virus gene”, etc., is shown. It is shown how post-genomic technologies will make it possible to find informative biomarkers of severe coronavirus infection, including those based on complex immune disorders associated with COVID-19.
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##article.viewOnOriginalSite##About the authors
Ivan Yu. Torshin
Federal Research Center “Computer Science and Control” of the Russian Academy of Sciences
Email: tiy135@gmail.com
ORCID iD: 0000-0002-2659-7998
канд. физ.-мат. наук, канд. хим. наук, вед. науч. сотр. ФИЦ ИУ РАН
Russian Federation, MoscowOlga A. Gromova
Federal Research Center “Computer Science and Control” of the Russian Academy of Sciences
Author for correspondence.
Email: unesco.gromova@gmail.com
ORCID iD: 0000-0002-7663-710X
SPIN-code: 6317-9833
д-р мед. наук, проф., вед. науч. сотр. ФИЦ ИУ РАН
Russian Federation, MoscowAlexander G. Chuchalin
Pirogov Russian National Research Medical University
Email: pulmomoskva@mail.ru
ORCID iD: 0000-0002-5070-5450
акад. РАН, д-р мед. наук, проф., зав. каф. госпитальной терапии педиатрического фак-та ФГАОУ ВО «РНИМУ им. Н.И. Пирогова»
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