Contrast-enhanced ultrasound: history, application and perspectives

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Abstract

The article discusses the stages of formation and development of ultrasound diagnostics, including those with contrast enhancement. The main types of contrast agents and their mechanism of action are presented. Examples of the use of contrast-enhanced ultrasound in various fields of medicine are given. The prospects of the method and its place in clinical practice are discussed.

About the authors

Olga Iu. Mironova

Sechenov First Moscow State Medical University (Sechenov University)

Email: mironova_o_yu@staff.sechenov.ru
ORCID iD: 0000-0002-5820-1759

доктор мед. наук, проф. каф. факультетской терапии №1

Russian Federation, Moscow

Maria A. Isaikina

Sechenov First Moscow State Medical University (Sechenov University)

Email: mironova_o_yu@staff.sechenov.ru
ORCID iD: 0000-0001-6440-8636

канд. мед. наук, ассистент каф. факультетской терапии №1 Институт клинической медицины им. Н.В. Склифосовского

Russian Federation, Moscow

Georgy O. Isaev

Sechenov First Moscow State Medical University (Sechenov University)

Author for correspondence.
Email: mironova_o_yu@staff.sechenov.ru
ORCID iD: 0000-0002-4871-8797

аспирант каф. факультетской терапии №1 Институт клинической медицины им. Н.В. Склифосовского

Russian Federation, Moscow

Maria V. Berdysheva

Sechenov First Moscow State Medical University (Sechenov University)

Email: mironova_o_yu@staff.sechenov.ru
ORCID iD: 0000-0002-3393-6863

студентка

Russian Federation, Moscow

Victor V. Fomin

Sechenov First Moscow State Medical University (Sechenov University)

Email: mironova_o_yu@staff.sechenov.ru
ORCID iD: 0000-0002-2682-4417

чл.-кор. РАН, доктор мед. наук, проф., проректор по клинической работе и дополнительному профессиональному образованию, зав. каф. факультетской терапии №1 Институт клинической медицины им. Н.В. Склифосовского

Russian Federation, Moscow

References

  1. Wiener WR, Lausen GD. Audition for the Traveler Who Is Visually Impaired. In: Eds. BB Blasch, WR Wiener, RL Welsch. Foundations of Orientation and Mobility. New York: AFB Press, 1997; p. 146.
  2. Marinesco N, Trillat JJ. Action des ultrasons sur les plaques photographique. C R Acad Sci. 1933;196:858-60.
  3. Marinesco N. Propriétés piézo-chimiques, physiques et biophysiques des ultrasons. I et II. Actualités scientifiques et industrielles. 522 & 523. Paris: Hermann, 1937.
  4. Dussik K. Über die Möglichkeit hochfrequente mechanische Schwingungen als diagnostiches Hilfsmittel zi verwenden. Z Neur. 1942;174:153.
  5. Dussik K. Ultraschallanwendung in der Diagnostik und Therapie des Erkrankungen des zentralen Nervensus-sytems. Ultrasch in der Med. 1949;1:283.
  6. Howry DH, Bliss WR. Ultrasonic visualization of soft tissue structures of the body. J Lab Clin Med. 1952;40:579-92.
  7. Strandness DE Jr., McCutcheon EP, Rushmer RF. Application of a transcutaneous Doppler flowmeter in evaluation of occlusive arterial disease. Surg Gynecol Obstet. 1966;122(5):1039-45.
  8. Leksell L. Echoencephalography I. Detection of intracranial complications following head injury. Acta Chir Scandinav. 1955;110:301.
  9. Edler I, Hertz CH. The use of ultrasonic reflectoscope for the continuous recording of movements of heart walls. Kungl Fysiogr Sällsk i Lund firhandl. 1954;24:5.
  10. Satomura S. Ultrasonic Doppler Method for the Inspection of Cardiac Functions. J Acoust Soc Am. 1957;29(11):1181-5. doi: 10.1121/1.1908737
  11. Kasai C, Namekawa K, Koyano A, Omoto R. Real-Time Two-Dimensional Blood Flow Imaging Using an Autocorrelation Technique. IEEE Transactions on Sonics and Ultrasonics. 1985;32(3):458-64. doi: 10.1109/T-SU.1985.31615
  12. Gramiak R, Shah P. Echocardiography of the aortic root. Invest Radiol. 1968;3:356-66.
  13. Enhancing the Role of Ultrasound with Contrast Agents. Ed. R Lencioni. Springer, 2006; p. 262.
  14. Feinstein SB, Shah PM, Bing RJ, et al. Microbubble dynamics visualized in the intact capillary circulation. J Am Coll Cardiol. 1984;4(3):595-600. doi: 10.1016/s0735-1097(84)80107-2
  15. Schürmann R, Schlief R. Saccharide-based contrast agents. Characteristics and diagnostic potential. Radiol Med. 1994;87(5 Suppl. 1):15-23.
  16. Kalantarinia K, Okusa MD. Ultrasound contrast agents in the study of kidney function in health and disease. Drug Discov Today Dis Mech. 2007;4(3):153-8. doi: 10.1016/j.ddmec.2007.10.006
  17. Qin S, Caskey CF, Ferrara KW. Ultrasound contrast microbubbles in imaging and therapy: physical principles and engineering. Phys Med Biol. 2009;54(6):R27-57. doi: 10.1088/0031-9155/54/6/R01
  18. Wei K, Mulvagh SL, Carson L, et al. The safety of deFinity and Optison for ultrasound image enhancement: a retrospective analysis of 78,383 administered contrast doses. J Am Soc Echocardiogr. 2008;21(11):1202-6. doi: 10.1016/j.echo.2008.07.019
  19. Lindner JR. Contrast echocardiography: current status and future directions. Heart. 2021;107(1):18-24. doi: 10.1136/heartjnl-2020-316662
  20. Porter TR, Mulvagh SL, Abdelmoneim SS, et al. Clinical Applications of Ultrasonic Enhancing Agents in Echocardiography: 2018 American Society of Echocardiography Guidelines Update. J Am Soc Echocardiogr. 2018;31(3):241-74. doi: 10.1016/j.echo.2017.11.013
  21. Levey AS, Cattran D, Friedman A, et al. Proteinuria as a surrogate outcome in CKD: report of a scientific workshop sponsored by the National Kidney Foundation and the US Food and Drug Administration. Am J Kidney Dis. 2009;54(2):205-26. doi: 10.1053/j.ajkd.2009.04.029
  22. Jeong S, Park SB, Kim SH, et al. Clinical significance of contrast-enhanced ultrasound in chronic kidney disease: a pilot study. J Ultrasound. 2019;22(4):453-60. doi: 10.1007/s40477-019-00409-x
  23. Wang L, Xia P, Lv K, et al. Assessment of renal tissue elasticity by acoustic radiation force impulse quantification with histopathological correlation: preliminary experience in chronic kidney disease. Eur Radiol. 2014;24(7):1694-9. doi: 10.1007/s00330-014-3162-5
  24. Claudon M, Dietrich CF, Choi BI, et al. Guidelines and good clinical practice recommendations for contrast enhanced ultrasound (CEUS) in the liver – update 2012: a WFUMB-EFSUMB initiative in cooperation with representatives of AFSUMB, AIUM, ASUM, FLAUS and ICUS. Ultraschall Med. 2013;34(1):11-29. doi: 10.1055/s-0032-1325499
  25. Erlichman DB, Weiss A, Koenigsberg M, Stein MW. Contrast enhanced ultrasound: A review of radiology applications. Clin Imaging. 2020;60(2):209-15. doi: 10.1016/j.clinimag.2019.12.013
  26. Bansal M, Kasliwal RR. Echocardiography for left atrial appendage structure and function. Indian Heart J. 2012;64(5):469-75. doi: 10.1016/j.ihj.2012.07.020
  27. Eriksson MJ, Sonnenberg B, Woo A, et al. Long-term outcome in patients with apical hypertrophic cardiomyopathy. J Am Coll Cardiol. 2002;39(4):638-45. doi: 10.1016/s0735-1097(01)01778-8
  28. Hoffmann R, Barletta G, von Bardeleben S, et al. Analysis of left ventricular volumes and function: a multicenter comparison of cardiac magnetic resonance imaging, cine ventriculography, and unenhanced and contrast-enhanced two-dimensional and three-dimensional echocardiography. J Am Soc Echocardiogr. 2014;27(3):292-301. doi: 10.1016/j.echo.2013.12.005
  29. Kurt M, Shaikh KA, Peterson L, et al. Impact of contrast echocardiography on evaluation of ventricular function and clinical management in a large prospective cohort. J Am Coll Cardiol. 2009;53(9):802-10. doi: 10.1016/j.jacc.2009.01.005
  30. Ogbogu PU, Rosing DR, Horne MK 3rd. Cardiovascular manifestations of hypereosinophilic syndromes. Immunol Allergy Clin North Am. 2007;27(3):457-75. doi: 10.1016/j.iac.2007.07.001
  31. Vos HJ, Voorneveld JD, Groot Jebbink E, et al. Contrast-Enhanced High-Frame-Rate Ultrasound Imaging of Flow Patterns in Cardiac Chambers and Deep Vessels. Ultrasound Med Biol. 2020;46(11):2875-90. doi: 10.1016/j.ultrasmedbio.2020.07.022
  32. Frinking P, Segers T, Luan Y, Tranquart F. Three Decades of Ultrasound Contrast Agents: A Review of the Past, Present and Future Improvements. Ultrasound Med Biol. 2020;46(4):892-908. doi: 10.1016/j.ultrasmedbio.2019.12.008
  33. Nittayacharn P, Yuan HX, Hernandez C, et al. Enhancing Tumor Drug Distribution With Ultrasound-Triggered Nanobubbles. J Pharm Sci. 2019;108(9):3091-8. doi: 10.1016/j.xphs.2019.05.004
  34. Chong WK, Papadopoulou V, Dayton PA. Imaging with ultrasound contrast agents: current status and future. Abdom Radiol (NY). 2018;43(4):762-72. doi: 10.1007/s00261-018-1516-1.

Supplementary files

Supplementary Files
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1. JATS XML
2. Fig. 1. Ultrasonic device created by Douglas Howry and Joseph Holmes, from the University of Colorado [7].

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3. Fig. 2. The phenomenon of microbubbles cavitation observed in videomicroscopy [18].

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4. Fig. 3. Comparison of standard EchoCG (a, d), contrast-enhanced EchoCG (b, e) and MRI in patients with hypertrophic cardiomyopathy (c, f) [31].

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