Frontal dynamics of erythromycin sorption on monolithic molecularly imprinted polymer sorbents

Abstract

The effect the flow rate of a mobile phase has on the frontal dynamics of antibiotic erythromycin sorption by monolithic molecularly imprinted polymeric sorbents based on 2-hydroxyethyl methacrylate and ethylene glycol dimethacrylate and their non-imprinted analog is studied. It is shown that erythromycin sorption proceeds in both the interglobular and intraglobular space of monolithic matrices, and the dynamic capacity of sorption can be regulated by changing the time of the experiment. The mobile phase flow rate at which the maximum specific bonding of the antibiotic by molecularly imprinted monolithic sorbents is observed is determined.