Synthesis and Characterization of 3-Hydroxy-2-(5'-Hydroxypentyl)-4H-Pyran-4-one and Study of Its Complexation with Iron(III)

详细

With the special focus to obtain a new tridentate ligand able to coordinate Fe(III), 3-hydroxy-2-(5'-hydroxypentyl)-4H-pyran-4-one (5-H) has been synthesized. Iron/ligand solution chemistry has been investigated in aqueous solution by ESI-MS and cyclic voltammetric measurements. The physiologic predominant specie is the tris-chelate complex as Job test attested. The electrode potential of the [Fe^III(5)₃]/[Fe^II(5)₃]^– couple was evaluated to be –0.54 V vs. SCE, pH 7.4.