The influence of the sizes of nanodiamond aggregates in their suspensions on the efficiency of sorption of  90 Y and  177 Lu isotopes for their subsequent use in nuclear medicine

A. G. Kazakov; Казаков А. Г.; J. S. Babenya; Бабеня Ю. С.; T. Y. Ekatova; Екатова Т. Ю.; S. E. Vinokurov; Винокуров С. Е.; E. Y. Khvorostinin; Хворостинин Е. Ю.; I. A. Ushakov; Ушаков И. А.; V. V. Zukau; Зукау В. В.; E. S. Stasyuk; Стасюк Е. С.; E. A. Nesterov; Нестеров Е. А.; V. L. Sadkin; Садкин В. Л.; A. S. Rogov; Рогов А. С.; B. F. Myasoedov; Мясоедов Б. Ф.

doi:10.31857/S0033831124020093

The influence of the sizes of nanodiamond aggregates in their suspensions on the efficiency of sorption of ⁹⁰Y and ¹⁷⁷Lu isotopes for their subsequent use in nuclear medicine

作者: Kazakov A.¹, Babenya J.¹, Ekatova T.¹, Vinokurov S.¹, Khvorostinin E.¹, Ushakov I.², Zukau V.², Stasyuk E.², Nesterov E.², Sadkin V.², Rogov A.², Myasoedov B.¹^,3
隶属关系:
1. Vernadsky Institute of Geochemistry and Analytical Chemistry, Russian Academy of Sciences
2. National Research Tomsk Polytechnic University
3. Interdepartmental Center for Analytical Research in Physics, Chemistry and Biology, Russian Academy of Sciences
期: 卷 66, 编号 2 (2024)
页面: 178–184
栏目: Articles
URL: https://journals.rcsi.science/0033-8311/article/view/263863
DOI: https://doi.org/10.31857/S0033831124020093
ID: 263863

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Nanodiamonds (NDs) are promising carriers of radionuclides in radiopharmaceuticals for use in nuclear medicine. In this work, we investigated the influence of the properties of ND suspensions, including the sizes of their aggregates, in aqueous solutions with different pH on their binding of medical isotopes ⁹⁰Y and ¹⁷⁷Lu and found the conditions for obtaining promising conjugates for further in vivo studies. It was shown that sorption is influenced by the composition of the solution, which determines the properties of the ND surface, while the forms of cations of the studied nuclides in the solution do not affect the degree of sorption.

关键词

yttrium-90, lutetium-177, nanodiamonds, sorption, aggregate sizes, dynamic light scattering

参考

Chauhan S., Neha J., Nagaich U. // J. Pharm. Anal. 2020. Vol. 10. N 1. P. 1–12.
Wang X., Sang D., Zou L., Ge S., Yao Y., Fan J., Wang Q. // Molecules. 2023. Vol. 28. N 10. Article 4063.
Kazakov A.G., Garashchenko B.L., Yakovlev R.Y., Vinokurov S.E., Kalmykov S.N., Myasoedov B.F. // Diam. Relat. Mater. 2020. Vol. 104. Article 107752.
Kazakov A.G., Garashchenko B.L., Yakovlev R.Y., Vinokurov S.E., Myasoedov B.F. // Radiochemistry. 2020. Vol. 62. P. 752–758.
Kazakov A.G., Garashchenko B.L., Ivanova M.K., Vinokurov S.E., Myasoedov B.F. // Nanomaterials. 2020. Vol. 10. N 6. Article 1090.
Babenya J.S., Kazakov A.G., Ekatova T.Y., Yakovlev R.Y. // J Radioanal Nucl Chem. 2021. Vol. 329. N 2. P. 1027–1031.
Казаков А.Г., Бабеня Ю.С., Екатова Т.Ю., Винокуров С.Е., Ушаков И.А., Зукау В.В., Стасюк Е.С., Нестеров Е.А., Садкин В.Л., Рогов А.С., Мясоедов Б.Ф. // Радиохимия. 2024. Т. 66. № 2. *СТАТЬЯ 10137*.
Chaudhuri A., Kumar D.N., Dehari D., Singh S., Kumar P., Bolla P.K. et al. // Pharmaceuticals. 2022. Vol. 15. Article 542.
Srinivas S.M., Nasr E.C., Kunam V.K., Bullen J.A., Purysko A.S. // J. Gastrointest. Oncol. 2016. Vol. 7. N 4. P. 530–539.
Kazakov A.G., Babenya J.S., Ekatova T.Y., Vinokurov S.E., Myasoedov B.F. // Advances in Geochemistry, Analytical Chemistry and Planetary Sciences. 2023. P. 595–601.
Yakovlev R.Y., Dogadkin N.N., Kulakova I.I., Lisichkin G.V., Leonidov N.B., Kolotov V.P. // Diam. Relat. Mater. 2015. Vol. 55. P. 77–86.
Karpukhin A.V., Avkhacheva N.V., Yakovlev R.Y., Kulakova I.I., Yashin V.A., Lisichkin G.V., Safronova V.G. // Cell. Biol. Int. 2011. Vol. 35. N 7. P. 727–733.
Dolmatov V.Y., Rudenko D.V., Burkat G.K., Aleksandrova A.S., Vul’ A.Yu., Aleksenskii A.E. et al. // J. Superhard Mater. 2019. Vol. 41. N 3. P. 169–177.
Pichot V., Comet M., Fousson E., Baras C., Senger A., Normand F.L., Spitzer D. // Diam. Relat. Mater. 2008. Vol. 17. N 1. P. 13–22.
Buchatskaya Y., Romanchuk A., Yakovlev R., Shiryaev A., Kulakova I., Kalmykov S. // Radiochim. Acta. 2015. Vol. 103. N 3. P. 205–211.
Zhukov A.N., Shvidchenko A.V., Yudina E.B. // Colloid J. 2020. Vol. 82. N 4. P. 369–375.
Shvidchenko A.V., Zhukov A.N., Dideikin A.T., Baidakova M.V., Shestakov M.S., Shnitov V.V. Vul’ A.Y. // Colloid J. 2016. Vol. 78. N 2. P. 235–241.
Winter G., Eberhardt N., Löffler J., Raabe M., Alam M.N.A., Hao L. et al. // Nanomaterials. 2022. Vol. 12. N 24. Article 4471.
Verweij W. // CHEAQS Next vers. 0.2.1.10. https://www.cheaqs.eu/

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The influence of the sizes of nanodiamond aggregates in their suspensions on the efficiency of sorption of ⁹⁰Y and ¹⁷⁷Lu isotopes for their subsequent use in nuclear medicine

全文:

详细

关键词

作者简介

A. Kazakov

J. Babenya

T. Ekatova

S. Vinokurov

E. Khvorostinin

I. Ushakov

V. Zukau

E. Stasyuk

E. Nesterov

V. Sadkin

A. Rogov

B. Myasoedov

参考

The influence of the sizes of nanodiamond aggregates in their suspensions on the efficiency of sorption of 90Y and 177Lu isotopes for their subsequent use in nuclear medicine

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The influence of the sizes of nanodiamond aggregates in their suspensions on the efficiency of sorption of ⁹⁰Y and ¹⁷⁷Lu isotopes for their subsequent use in nuclear medicine