On the possibility of determining anthracycline antibiotics in aqueous solutions using optical analytical system (biosensor)
- Авторы: Yevdokimov Y.M.1, Skuridin S.G.1, Salyanov V.I.1, Semenov S.V.2, Sol’ev P.N.1, Valuev-Elliston V.T.1, Vereshchagin F.V.3, Chulkov D.P.3, Kompanets O.N.3
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Учреждения:
- Engelhardt Institute of Molecular Biology
- Russian Research Centre Kurchatov Institute
- Institute of Spectroscopy
- Выпуск: Том 122, № 2 (2017)
- Страницы: 194-201
- Раздел: Condensed-Matter Spectroscopy
- URL: https://journals.rcsi.science/0030-400X/article/view/165319
- DOI: https://doi.org/10.1134/S0030400X17020096
- ID: 165319
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Аннотация
We propose a version of the theory describing the circular dichroism spectra of cholesteric liquidcrystal dispersion particles of double-stranded DNA. The basis of the theory is the concept of absorption of electromagnetic waves by large molecular systems. The effect of physical parameters of dispersion particles on their circular dichroism is theoretically determined. It is experimentally demonstrated that circular dichroism can be used as a convenient tool for creating an optical analytical system for the determination of biologically active compounds that interact with DNA molecules.
Об авторах
Yu. Yevdokimov
Engelhardt Institute of Molecular Biology
Автор, ответственный за переписку.
Email: yevdokim@eimb.ru
Россия, Moscow, 119991
S. Skuridin
Engelhardt Institute of Molecular Biology
Email: yevdokim@eimb.ru
Россия, Moscow, 119991
V. Salyanov
Engelhardt Institute of Molecular Biology
Email: yevdokim@eimb.ru
Россия, Moscow, 119991
S. Semenov
Russian Research Centre Kurchatov Institute
Email: yevdokim@eimb.ru
Россия, Troitsk, Moscow, 108840
P. Sol’ev
Engelhardt Institute of Molecular Biology
Email: yevdokim@eimb.ru
Россия, Moscow, 119991
V. Valuev-Elliston
Engelhardt Institute of Molecular Biology
Email: yevdokim@eimb.ru
Россия, Moscow, 119991
F. Vereshchagin
Institute of Spectroscopy
Email: yevdokim@eimb.ru
Россия, Troitsk, Moscow, 142190
D. Chulkov
Institute of Spectroscopy
Email: yevdokim@eimb.ru
Россия, Troitsk, Moscow, 142190
O. Kompanets
Institute of Spectroscopy
Email: yevdokim@eimb.ru
Россия, Troitsk, Moscow, 142190
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