Autowave Self-Organization in the Folding of Proteins
- Авторлар: Sidorova A.E.1, Levashova N.T.2, Malyshko E.V.1, Tverdislov V.A.1
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Мекемелер:
- Department of Biophysics, Faculty of Physics
- Department of Mathematics, Faculty of Physics
- Шығарылым: Том 74, № 3 (2019)
- Беттер: 213-226
- Бөлім: Biophysics and Medical Physics (Review)
- URL: https://journals.rcsi.science/0027-1349/article/view/165119
- DOI: https://doi.org/10.3103/S0027134919030135
- ID: 165119
Дәйексөз келтіру
Аннотация
A review of physical regularities in formation of the the spatial structure of proteins during their folding, that is, the folding of a homochiral polypeptide chain into a unique native configuration, is presented, including the mathematical models of this process. The materials of this review are summarized in a new phenomenological model for the formation of hierarchies of sign-alternating chiral structures and also in a new mathematical model for the formation of α-helices as autowave structures. Some folding thermodynamic aspects associated with symmetry factors are discussed.
Негізгі сөздер
Авторлар туралы
A. Sidorova
Department of Biophysics, Faculty of Physics
Хат алмасуға жауапты Автор.
Email: sky314bone@mail.ru
Ресей, Moscow, 119991
N. Levashova
Department of Mathematics, Faculty of Physics
Email: katyamalyshko@mail.ru
Ресей, Moscow, 119991
E. Malyshko
Department of Biophysics, Faculty of Physics
Хат алмасуға жауапты Автор.
Email: katyamalyshko@mail.ru
Ресей, Moscow, 119991
V. Tverdislov
Department of Biophysics, Faculty of Physics
Email: katyamalyshko@mail.ru
Ресей, Moscow, 119991
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