Email this article Observation of Brownian relaxation of magnetic nanoparticles using HTS SQUID
- Authors: Snigirev O.V.1, Soloviev I.I.2, Kalabukhov A.S.2,3, Chukharkin M.L.3
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Affiliations:
- Department of Semiconductor Physics, Faculty of Physics
- Skobeltsyn Institute of Nuclear Physics
- Chalmers University of Technology
- Issue: Vol 72, No 1 (2017)
- Pages: 95-100
- Section: Biophysics and Medical Physics
- URL: https://journals.rcsi.science/0027-1349/article/view/164710
- DOI: https://doi.org/10.3103/S0027134917010143
- ID: 164710
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Abstract
We analyzed the sensitivity of a separationless immunoassay scheme using functionalized magnetic nanoparticles (MNPs) and a sensitive HTS SQUID magnetometer. The signal of a 100 μL sample at a concentration of 1 mg/mL and field of 7.5 nT was 20 mΦ0. This makes it possible for the sensitivity to be within the range of 50 ng/mL at the required time of up to 100 s per a point in the frequency spectrum.
About the authors
O. V. Snigirev
Department of Semiconductor Physics, Faculty of Physics
Author for correspondence.
Email: oleg.snigirev@phys.msu.ru
Russian Federation, Moscow, 119991
I. I. Soloviev
Skobeltsyn Institute of Nuclear Physics
Email: oleg.snigirev@phys.msu.ru
Russian Federation, Moscow, 119991
A. S. Kalabukhov
Skobeltsyn Institute of Nuclear Physics; Chalmers University of Technology
Email: oleg.snigirev@phys.msu.ru
Russian Federation, Moscow, 119991; Kemivagen 9, Gothenburg, SE 412 96
M. L. Chukharkin
Chalmers University of Technology
Email: oleg.snigirev@phys.msu.ru
Sweden, Kemivagen 9, Gothenburg, SE 412 96
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