Enviar artigo por via de e-mail The Common Partner of Several Methyltransferases Modifying the Components of The Eukaryotic Translation Apparatus
- Autores: Vasilieva E.N.1, Laptev I.G.2,3, Sergiev P.V.2,3, Dontsova O.A.2,3,4
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Afiliações:
- Faculty of Bioengineering and Bioinformatics, Moscow State University
- Faculty of Chemistry, Moscow State University
- Skolkovo Institute of Science and Technology
- Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
- Edição: Volume 52, Nº 6 (2018)
- Páginas: 846-853
- Seção: Reviews
- URL: https://journals.rcsi.science/0026-8933/article/view/163727
- DOI: https://doi.org/10.1134/S0026893318060171
- ID: 163727
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Resumo
TRM112 is necessary for the activation and stability of several methyltransferases involved in the modification of various components of the translation apparatus. This unique protein is a partner for enzymes that methylate tRNA, rRNA, and the translation termination factor. Here we review the structural and functional features of the TRM112 complexes with methyltransferases and provide, where possible, information on their significance.
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Sobre autores
E. Vasilieva
Faculty of Bioengineering and Bioinformatics, Moscow State University
Autor responsável pela correspondência
Email: elnvasv@gmail.com
Rússia, Moscow, 119991
I. Laptev
Faculty of Chemistry, Moscow State University; Skolkovo Institute of Science and Technology
Email: elnvasv@gmail.com
Rússia, Moscow, 119991; Skolkovo, 143026
P. Sergiev
Faculty of Chemistry, Moscow State University; Skolkovo Institute of Science and Technology
Email: elnvasv@gmail.com
Rússia, Moscow, 119991; Skolkovo, 143026
O. Dontsova
Faculty of Chemistry, Moscow State University; Skolkovo Institute of Science and Technology; Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
Email: elnvasv@gmail.com
Rússia, Moscow, 119991; Skolkovo, 143026; Moscow, 117997
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