Synthesis, Crystal Structures of Two Novel Metal Coordination Polymers and Study of Their Inhibition of Human Hemangioma Cells

Abstract

In this work, two new In^III-based coordination polymers {(H₂NMe₂)₃[In(TATAB)₂](H₂O)₆}_n (1, H₃TATAB = 4,4′,4″-s-triazine-1,3,5-triyl-tri-p-aminobenzoic acid) and {(Me₂NH₂)₂[In₂(TTA)₂(FA)₂] (DMF)₃}_n (2, H₃TTA = 4,4′,4″-{[(2,4,6-trimethylbenzene-1,3,5-triyl)tris(methylene)]tris(oxy)}tribenzoic acid, HFA = 2-fluorobenzoic acid, DMF = N,N-dimethylformamide) are successfully prepared under solvothermal conditions and structurally characterized by the single crystal X-ray study (SCXRD) and the powder X-ray analysis (PXRD). In addition, the in vitro anticancer activity of compounds 1 and 2 on three human hemangioma cells (HMEC-1, EAhy926 and SV40) is further investigated.