Synthesis and Antibacterial Activities of Novel Hg(II) and Zn(II) Complexes of Bis(Thiosemicarbazone) Acenaphthenequinone Loaded to MWCNTs


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Abstract

This paper describes a series of new polyamides containing bis(thiosemicarbazone) acenaphthenequinone (PA), bis(thiosemicarbazone) acenaphthenequinone zinc (Z-PA), and bis(thiosemicarbazone) acenaphthenequinone mercury (H-PA) complexes loaded onto MWCNTs synthesized via a chemical precipitation method in methanol followed by antimicrobial activity studies on the novel functionalized MWCNTs complexes. These complexes are characterized by FT-IR spectroscopy, powder X-ray diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). The antibacterial activity of free PA, Z-PA, and H-PA complexes loaded onto MWCNTs are studied against gram-positive and gram-negative bacteria. The results indicate that the HPA/MWCNT complex is the most effective growth inhibitor against Listeria monocytogenes and Pseudomonas aeruginosa, exhibiting the potential for the use as an antibacterial agent.

About the authors

N. Abdolhi

Golestan Rheumatology Research Center

Email: g.chem1983@gmail.com
Iran, Islamic Republic of, Gorgan

M. Aghaei

Golestan Rheumatology Research Center

Email: g.chem1983@gmail.com
Iran, Islamic Republic of, Gorgan

A. Soltani

Golestan Rheumatology Research Center

Author for correspondence.
Email: g.chem1983@gmail.com
Iran, Islamic Republic of, Gorgan

H. Mighani

Department of Chemistry, Faculty of Science

Email: g.chem1983@gmail.com
Iran, Islamic Republic of, Gorgan

E. A. Ghaemi

Department of Microbiology

Email: g.chem1983@gmail.com
Iran, Islamic Republic of, Gorgan

M. B. Javan

Department of Physics, Faculty of Science

Email: g.chem1983@gmail.com
Iran, Islamic Republic of, Gorgan

A. D. Khalaji

Department of Chemistry, Faculty of Science

Email: g.chem1983@gmail.com
Iran, Islamic Republic of, Gorgan

S. Sharbati

Golestan Rheumatology Research Center

Email: g.chem1983@gmail.com
Iran, Islamic Republic of, Gorgan

M. Shafipour

Department of Microbiology

Email: g.chem1983@gmail.com
Iran, Islamic Republic of, Gorgan

H. Balakheyli

Golestan Rheumatology Research Center

Email: g.chem1983@gmail.com
Iran, Islamic Republic of, Gorgan

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