On the Impact of Flow-Diverters on the Hemodynamics of Human Cerebral Aneurysms


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Abstract

The impact of flow-diverters used for cerebral aneurysm treatment on human brain hemodynamics was evaluated qualitatively and quantitatively. Numerical simulation of flow-diverter placement in cerebral vessels with aneurysms was carried out for the case history of a real patient using the commercial ANSYS 17.2 package with different (Newtonian and non-Newtonian) hydrodynamic models for blood rheology in different parts of the vessel and aneurysm, which is due to experimental data. It is shown that after flow-diverter placement, the blood flow through the artery segment containing the aneurysm neck decreases, resulting in a redistribution of the cerebral blood flow, which becomes close to the blood flow in healthy subjects. Changes in wall shear stresses in the flow-diverter region are indicative of possible aneurysm recanalization.

About the authors

D. V. Parshin

Lavrent’ev Institute of Hydrodynamics, Siberian Branch; Novosibirsk National Research State University

Author for correspondence.
Email: parshin@hydro.nsc.ru
Russian Federation, Novosibirsk, 630090; Novosibirsk, 630090

Yu. O. Kuyanova

Lavrent’ev Institute of Hydrodynamics, Siberian Branch; Novosibirsk National Research State University

Email: parshin@hydro.nsc.ru
Russian Federation, Novosibirsk, 630090; Novosibirsk, 630090

D. S. Kislitsin

Meshalkin National Medical Research Center

Email: parshin@hydro.nsc.ru
Russian Federation, Novosibirsk, 630055

U. Windberger

Center for Biomedical Research Vienna Medical University

Email: parshin@hydro.nsc.ru
Austria, Vienna, 1090

A. P. Chupakhin

Lavrent’ev Institute of Hydrodynamics, Siberian Branch; Novosibirsk National Research State University

Email: parshin@hydro.nsc.ru
Russian Federation, Novosibirsk, 630090; Novosibirsk, 630090

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