Numerical simulation of cerebrospinal fluid hydrodynamics in the healing process of hydrocephalus patients
- Authors: Gholampour S.1, Fatouraee N.2, Seddighi A.S.3, Seddighi A.3
-
Affiliations:
- Department of Biomedical Engineering, Science and Research Branch
- Biological Fluid Mechanics Research Laboratory, Biomechanics Department, Biomedical Engineering Faculty
- Functional Neurosurgery Research Center of Shohada Tajrish Hospital
- Issue: Vol 58, No 3 (2017)
- Pages: 386-391
- Section: Article
- URL: https://journals.rcsi.science/0021-8944/article/view/160064
- DOI: https://doi.org/10.1134/S0021894417030026
- ID: 160064
Cite item
Abstract
Three-dimensional computational models of the cerebrospinal fluid (CSF) flow and brain tissue are presented for evaluation of their hydrodynamic conditions before and after shunting for seven patients with non-communicating hydrocephalus. One healthy subject is also modeled to compare deviated patients data to normal conditions. The fluid-solid interaction simulation shows the CSF mean pressure and pressure amplitude (the superior index for evaluation of non-communicating hydrocephalus) in patients at a greater point than those in the healthy subject by 5.3 and 2 times, respectively.
About the authors
S. Gholampour
Department of Biomedical Engineering, Science and Research Branch
Author for correspondence.
Email: s.gholampour@srbiau.ac.ir
Iran, Islamic Republic of, Tehran
N. Fatouraee
Biological Fluid Mechanics Research Laboratory, Biomechanics Department, Biomedical Engineering Faculty
Email: s.gholampour@srbiau.ac.ir
Iran, Islamic Republic of, Tehran
A. S. Seddighi
Functional Neurosurgery Research Center of Shohada Tajrish Hospital
Email: s.gholampour@srbiau.ac.ir
Iran, Islamic Republic of, Tehran
A. Seddighi
Functional Neurosurgery Research Center of Shohada Tajrish Hospital
Email: s.gholampour@srbiau.ac.ir
Iran, Islamic Republic of, Tehran