Numerical simulation of cerebrospinal fluid hydrodynamics in the healing process of hydrocephalus patients


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Abstract

Three-dimensional computational models of the cerebrospinal fluid (CSF) flow and brain tissue are presented for evaluation of their hydrodynamic conditions before and after shunting for seven patients with non-communicating hydrocephalus. One healthy subject is also modeled to compare deviated patients data to normal conditions. The fluid-solid interaction simulation shows the CSF mean pressure and pressure amplitude (the superior index for evaluation of non-communicating hydrocephalus) in patients at a greater point than those in the healthy subject by 5.3 and 2 times, respectively.

About the authors

S. Gholampour

Department of Biomedical Engineering, Science and Research Branch

Author for correspondence.
Email: s.gholampour@srbiau.ac.ir
Iran, Islamic Republic of, Tehran

N. Fatouraee

Biological Fluid Mechanics Research Laboratory, Biomechanics Department, Biomedical Engineering Faculty

Email: s.gholampour@srbiau.ac.ir
Iran, Islamic Republic of, Tehran

A. S. Seddighi

Functional Neurosurgery Research Center of Shohada Tajrish Hospital

Email: s.gholampour@srbiau.ac.ir
Iran, Islamic Republic of, Tehran

A. Seddighi

Functional Neurosurgery Research Center of Shohada Tajrish Hospital

Email: s.gholampour@srbiau.ac.ir
Iran, Islamic Republic of, Tehran


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