Mitochondrial DNA Mutations in Cardiovascular Diseases
- Авторлар: Korepanov V.1, Rebrova T.1, Batalov R.1, Afanasiev S.1
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Мекемелер:
- Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Science
- Шығарылым: Том 59, № 7 (2023)
- Беттер: 735-740
- Бөлім: ОБЗОРНЫЕ И ТЕОРЕТИЧЕСКИЕ СТАТЬИ
- URL: https://journals.rcsi.science/0016-6758/article/view/134614
- DOI: https://doi.org/10.31857/S0016675823070068
- EDN: https://elibrary.ru/QKHDWL
- ID: 134614
Дәйексөз келтіру
Аннотация
Early prevention of development and timely diagnosis of diseases of the cardiovascular system are some of the main tasks of modern cardiology. One of the promising approaches is aimed at identifying associations between the carriage of mitochondrial DNA (mtDNA) mutations and the development of cardiovascular diseases. Mitochondria are the only source of energy accumulation in cardiomyocytes; therefore, failure of their functioning, caused by mtDNA mutations, directly affects the bioenergetics and the work of myocardial cells. The purpose of this review is to describe the current achivements in the study of associations of mutant mtDNA with the development of various pathologies of the cardiovascular system.
Негізгі сөздер
Авторлар туралы
V. Korepanov
Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Science
Хат алмасуға жауапты Автор.
Email: vakorep41811@gmail.com
Russia, 634012, Tomsk
T. Rebrova
Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Science
Email: vakorep41811@gmail.com
Russia, 634012, Tomsk
R. Batalov
Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Science
Email: vakorep41811@gmail.com
Russia, 634012, Tomsk
S. Afanasiev
Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Science
Email: vakorep41811@gmail.com
Russia, 634012, Tomsk
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