Flavonoid Glycosides in Leaves of Plants of the Genus Nigella L.

S. N. Shysh; Шиш С. Н.; P. S. Shabunya; Шабуня П. С.; S. A. Fatykhava; Фатыхова С. А.; V. N. Reshetnikov; Решетников В. Н.; E. V. Spirydovich; Спиридович Е. В.

doi:10.31857/S001533032360078X

Flavonoid Glycosides in Leaves of Plants of the Genus Nigella L.

作者: Shysh S.N.¹, Shabunya P.S.², Fatykhava S.A.², Reshetnikov V.N.¹, Spirydovich E.V.¹
隶属关系:
1. Central Botanical Garden, National Academy of Sciences of Belarus
2. Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus
期: 卷 70, 编号 7 (2023)
页面: 790-800
栏目: ЭКСПЕРИМЕНТАЛЬНЫЕ СТАТЬИ
URL: https://journals.rcsi.science/0015-3303/article/view/233782
DOI: https://doi.org/10.31857/S001533032360078X
EDN: https://elibrary.ru/ZQOXKH
ID: 233782

如何引用文章

全文:

开放存取

##reader.subscriptionAccessGranted##
受限制的访问

订阅存取

详细
作者简介
参考
补充文件
统计

详细

Phenolic compounds in plants of the genus Nigella are represented by various groups of flavonoids, gallocatechins, and derivatives of cinnamic and caffeic acids. The content of flavonoid glycosides in the leaves of Nigella damascena L., N. sativa L., and N. orientalis L. was established by the HPLC-MS method. Species-specific dependence of accumulation of flavonoid glycosides has been established. It was shown that the main flavonoids in the leaves of the studied objects were glycosides of quercetin and kaempferol, while quercetin glycosides were 1.40–1.97 times more than kaempferol in the studied extracts. N. sativa leaves had an increased composition of flavonoid glycosides compared to other studied species. The qualitative composition of N. damascena flavonoid glycosides was like N. sativa, whereas it is close to N. orientalis in terms of the total content of this group of compounds. Total amount of flavonoid glycosides in N. sativa leaf extracts was four times higher than in extracts of other types of Nigella. It is worth noting that the types N. sativa and N. damascena have the greatest phenotypic similarity and are more resistant to growing conditions in Belarus, while the species N. orientalis is different in appearance and more demanding on cultivation conditions. It was found that the variety of flavonoids glycosides in N. orientalis leaves is less in the absence of high molecular weight and acylated forms. The possible absence of acylated derivatives and less variety of flavonoids glycosides affects the low stability N. orientalis to abiotic factors and reduces its adaptive potential.

关键词

Nigella damascena L., Nigella orientalis L., Nigella sativa L., glycosides, leaves, flavonoids

参考

Дудченко Л.Г., Козьяков А.С., Кривенко В.В. Пряно-ароматические и пряно-вкусовые растения. Справочник. Киев: Наукова думка. 1989. 304 с.
Прохоров В.Н. Нигелла – ценная хозяйственно-полезная культура (обзор литературы) // Овощи России. 2021. Р. 111. https://doi.org/10.18619/2072-9146-2021-4-111-123
Datta A.K., Saha A. Cytomorphological studies and seed protein characterization of Nigella sativa L. and Nigella damascena L. // Cytologia (Tokyo). 2003. V. 68. P. 51.
Benazzouz-Smail L., Achat S., Brahmi F., Bachir-Bey M., Arab R., Lorenzo J.M., Benbouriche A., Boudiab K., Hauchard D., Boulekbache-Makhlouf L., Madani K. Biological properties, phenolic profile, and botanical aspect of Nigella sativa L. and Nigella damascena L. seeds // Molecules. 2023. V. 28. P. 571. https://doi.org/10.3390/molecules28020571
Bourgou S., Riadh K., Amor B., Ines S., Hanen F., Brahim M. Phenolic composition and biological activities of Tunisian Nigella sativa L. shoots and roots // C. R. Biol. 2008. V. 331. P. 48. https://doi.org/10.1016/j.crvi.2007.11.001
Исакова А.Л., Прохоров В.Н., Исаков А.В. Нигелла в Беларуси. Горки: БГСХА, 2021. 118 с.
Kokoska L., Havlik J., Valterova I., Nepovim A., Rada V., Vanek T. Chemical composition of the essential oil of Nigella orientalis L. seeds // Flavour Fragr. J. 2005. V. 20. P. 419. https://doi.org/10.1002/ffj.1449
Kökdil G., Tamer L., Ercan B., Celik M., Atik U. Effects of Nigella orientalis and N. segetalis fixed oils on blood biochemistry in rats // Phytother. Res. 2006. V. 20. P. 71. https://doi.org/10.1002/ptr.1809
Ait Eldjoudi D., Ruiz-Fernandez C., González-Rodriguez M., Ait Atmane S., Cordero-Barreal A., Farrag Y., Pino J., Sineiro J., Lago F., Conde-Aranda J., Khettal B., Gualillo O. Analgesic and antiinflammatory effects of Nigella orientalis L. seeds fixed oil: pharmacological potentials and molecular mechanisms // Phytother. Res. 2022. V. 36. P. 1372. https://doi.org/10.1002/ptr.7400
Gueffa A., Gonzalez-Serrano D.J., Christodoulou M.C., Orellana-Palacios J.C., Lopez S., Ortega M., Ouldmoumna A., Zohra Kiari F., Ioannou G.D., Kapnissi-Christodoulou C.P., Moreno A., Hadidi M. Phenolics from defatted black cumin seeds (Nigella sativa L.): ultrasound-assisted extraction optimization, comparison, and antioxidant activity // Biomolecules. 2022. V. 12. P. 1311. https://doi.org/10.3390/biom12091311
Topcagic A., Zeljkovic S.C., Karalija E., Galijasevic S., Sofic E. Evaluation of phenolic profile, enzyme inhibitory and antimicrobial activities of Nigella sativa L. seed extracts // Bosn. J. Basic Med. Sci. 2017. V. 17. P. 286. https://doi.org/10.17305/bjbms.2017.2049
Akram Khan M., Afzal M. Chemical composition of Nigella sativa Linn: part 2 recent advances // Inflammopharmacology. 2016. V. 24. P. 67. https://doi.org/10.1007/s10787-016-0262-7
Hameeda S., Imrana A., un Nisaa M., Arshada M.S., Saeeda F., Umair Arshada M., Khan M.A. Characterization of extracted phenolics from black cumin (Nigella sativa linn), coriander seed (Coriandrum sativum L.), and fenugreek seed (Trigonella foenum-graecum) // Int. J. Food Prop. 2019. V. 22. P. 714. https://doi.org/10.1080/10942912.2019.1599390
Шиш С.Н., Шутова А.Г., Спиридович Е.В., Шабуня П.С., Фатыхова С.А. Растения рода Nigella как источник ценных биологических веществ для биотехнологии // Материалы Международной научной конференции “Настоящее и будущее биотехнологии растений”, г. Минск, 2023. С. 98.
Ansary J., Regolo L., Machì M., Salinari A. Cianciosi D. Evaluation of the in vitro bioaccessibility of phenolic compounds of black cumin (BARI-1 cumin) methanolic extract // eFood. 2022. V. 3:e15. https://doi.org/10.1002/efd2.15
Parveen A., Farooq M.A., Kyunn W.W. A new oleanane type saponin from the aerial parts of Nigella sativa with anti-oxidant and anti-diabetic potential // Molecules. 2020. V. 25. P. 2171. https://doi.org/10.3390/molecules25092171
Dalli M., Bekkouch O., Azizi S., Azghar A., Gseyra N., Kim B. Nigella sativa L. phytochemistry and pharmacological activities: a review (2019-2021) // Biomolecules. 2022. V. 12. P. 20. https://doi.org/10.3390/biom12010020
Liu Y.M., Liu Q.H., Chen B.Q. A new flavonol glycoside from the seeds of Nigella glandulifera // Nat. Prod. Res. 2011. V. 25. P. 1334. https://doi.org/10.1080/14786419.2010.534470
Pinheiro P.F., Justino G.C. Structural analysis of flavonoids and related compounds – a review of spectroscopic applications // Phytochemicals – a global perspective of their role in nutrition and health / Ed. V. Rao. InTech. 2012. P. 33. https://doi.org/10.5772/29152
Alseekh S., Perez de Souza L., Benina M., Fernie A.R. The style and substance of plant flavonoid decoration; towards defining both structure and function // Phytochem. 2020. V. 174. P. 112347. https://doi.org/10.1016/j.phytochem.2020.112347
Юхимук А.Н., Тхань Л.Н., Спиридович Е.В. Молекулярно-генетический анализ некоторых видов рода чернушка (Nigella L.) // Cборник материалов II международной научно–практической конференции “Биотехнология: достижения и перспективы развития”. Пинск. 2017. С. 53.