Kinetics of Chemical Processes in the Human Brain: Modeling of the BOLD fMRI Signal


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Resumo

A kinetic model is presented that describes the pulse of the oxygen level increase in the excited nervous tissue of the human brain in response to an external signal. The model is based on biochemical data and describes experimental data on the hemodynamic impulse response. The model predicts the dynamic behavior of process participants preceding the oxygen pulse and determining the BOLD signal level.

Sobre autores

S. Varfolomeev

Institute of Physicochemical Foundations of the Functioning of Neural Network and Artificial Intelligence, Moscow State University

Email: vibykov@mail.ru
Rússia, Moscow, 119991

N. Semenova

Emanuel Institute of Biochemical Physics, Russian Academy of Sciences

Email: vibykov@mail.ru
Rússia, Moscow, 119991

V. Bykov

Emanuel Institute of Biochemical Physics, Russian Academy of Sciences

Autor responsável pela correspondência
Email: vibykov@mail.ru
Rússia, Moscow, 119991

S. Tsybenova

Emanuel Institute of Biochemical Physics, Russian Academy of Sciences

Email: vibykov@mail.ru
Rússia, Moscow, 119991

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