The relationship between self-organization and membrane effects of aqueous dispersion systems of the thyroliberin oligopeptide
- Авторлар: Konovalov A.I.1, Ryzhkina I.S.1, Pal’mina N.P.2, Mal’tseva E.L.3, Sergeeva S.Y.1, Murtazina L.I.1, Salakhutdinova O.A.1, Shevelev M.D.4, Zhernovkov V.E.2
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Мекемелер:
- Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
- Emanuel Institute of Biochemical Physics
- Doklady Akademii Nauk
- Kazan (Volga Region) Federal University
- Шығарылым: Том 474, № 1 (2017)
- Беттер: 80-84
- Бөлім: Physical Chemistry
- URL: https://journals.rcsi.science/0012-5016/article/view/153645
- DOI: https://doi.org/10.1134/S0012501617050025
- ID: 153645
Дәйексөз келтіру
Аннотация
The relationship between rearrangement of the dispersed phase inducing considerable changes in the pH and nonmonotonic concentration dependences of membrane effects in aqueous systems of the endogenous regulatory peptide, thyroliberin (thyrotropin-releasing hormone), in 10–3–10–16 mol/L concentration range was demonstrated for the first time. The membrane structure modification in the 10–13–10–16 mol/L range was found to be due to accumulation of nanoassociates, while the oppositely directed pronounced structural changes in the 10–6–10–12 mol/L range may be associated with the coexistence and rearrangement of dispersed phases of various nature (domains and associates) whose action on membrane lipid components is regulated in this concentration range by the correlated changes in the dispersed phase parameters and pH.
Авторлар туралы
A. Konovalov
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Email: ryzhkina@iopc.ru
Ресей, Kazan, 420088
I. Ryzhkina
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Хат алмасуға жауапты Автор.
Email: ryzhkina@iopc.ru
Ресей, Kazan, 420088
N. Pal’mina
Emanuel Institute of Biochemical Physics
Email: ryzhkina@iopc.ru
Ресей, Moscow, 117977
E. Mal’tseva
Doklady Akademii Nauk
Email: ryzhkina@iopc.ru
Ресей, ul. Profsoyuznaya 90, Moscow, 117997
S. Sergeeva
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Email: ryzhkina@iopc.ru
Ресей, Kazan, 420088
L. Murtazina
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Email: ryzhkina@iopc.ru
Ресей, Kazan, 420088
O. Salakhutdinova
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Email: ryzhkina@iopc.ru
Ресей, Kazan, 420088
M. Shevelev
Kazan (Volga Region) Federal University
Email: ryzhkina@iopc.ru
Ресей, Kazan, 420008
V. Zhernovkov
Emanuel Institute of Biochemical Physics
Email: ryzhkina@iopc.ru
Ресей, Moscow, 117977
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