Biocompatibility of the Ti81Nb13Ta3Zr3 Alloy


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Titanium-based alloy with low-toxic metals such as niobium, tantalum and zirconium (TiNbTaZr) was manufactured. The primary weight percentages of elements used for fusion were: titanium, 65%; niobium, 20%, tantalum, 10%; and zirconium, 5%. The TiNbTaZr alloy had a yield strength of about 550 MPa, a tensile strength of about 700 MPa, and a Young’s modulus of about 50 GPa, that is, it was comparable with Nitinol. A primary study of the biocompatibility of the TiNbTaZr alloy using the SH-SY5Y cells showed that the alloy did not have significant short-term toxicicity towards the cells incubated on the alloy surface. The number of non-viable cells was 2.5 times lower on the TiNbTaZr alloy than on Nitinol. The biocompatibility of TiNbTaZr was more pronounced than that of the Nitinol reference sample.

作者简介

M. Sevostyanov

Baikov Institute of Metallurgy and Materials Science

编辑信件的主要联系方式.
Email: cmakp@mail.ru
俄罗斯联邦, Moscow, 119334

A. Baikin

Baikov Institute of Metallurgy and Materials Science

Email: cmakp@mail.ru
俄罗斯联邦, Moscow, 119334

L. Shatova

Voronezh State Technical University (VSTU)

Email: cmakp@mail.ru
俄罗斯联邦, Voronezh, 394000

E. Nasakina

Baikov Institute of Metallurgy and Materials Science

Email: cmakp@mail.ru
俄罗斯联邦, Moscow, 119334

A. Berezhnov

Institute of Cell Biophysics

Email: cmakp@mail.ru
俄罗斯联邦, Pushchino, Moscow oblast, 142292

S. Gudkov

Prokhorov General Physics Institute; Vladmirsky Moscow Regional Research and Clinical Institute (MONIKI); All-Russian Research Institute of Phytopathology

Email: cmakp@mail.ru
俄罗斯联邦, Moscow, 119991; Moscow, 129110; Bolshie Vyaziomy, Moscow oblast

K. Sergienko

Baikov Institute of Metallurgy and Materials Science

Email: cmakp@mail.ru
俄罗斯联邦, Moscow, 119334

S. Konushkin

Baikov Institute of Metallurgy and Materials Science

Email: cmakp@mail.ru
俄罗斯联邦, Moscow, 119334

M. Baskakova

Baikov Institute of Metallurgy and Materials Science

Email: cmakp@mail.ru
俄罗斯联邦, Moscow, 119334

A. Kolmakov

Baikov Institute of Metallurgy and Materials Science

Email: cmakp@mail.ru
俄罗斯联邦, Moscow, 119334

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