Hydrogels and Sponge Materials Based on Triblock Copolymers of Lactide and Ethylene Glycol
- Authors: Zagoskin Y.D.1, Grigoriev T.E.1, Krasheninnikov S.V.1, Cuevda E.V.2, Gubareva E.A.2, Bakirov A.V.1,3, Chvalun S.N.1,3
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Affiliations:
- National Research Center “Kurchatov Institute”
- Kuban State Medical University, Ministry of Health of Russia
- Enikolopov Institute of Synthetic Polymeric Materials, Russian Academy of Sciences
- Issue: Vol 486, No 2 (2019)
- Pages: 149-151
- Section: Chemistry
- URL: https://journals.rcsi.science/0012-5008/article/view/154448
- DOI: https://doi.org/10.1134/S001250081906003X
- ID: 154448
Cite item
Abstract
New techniques were developed for the preparation of spongy materials and hydrogels based on triblock copolymers of lactide and ethylene glycol with various molecular structures. The effect of composition of the initial copolymers and supramolecular structure on their mechanical characteristics and biocompatibility was studied. According to cytological studies, all materials had a high level of cell viability (CV). The possibility of obtaining hydrogels with elastic moduli of up to 4460 kPa, which is a record high value for such systems, was demonstrated.
About the authors
Yu. D. Zagoskin
National Research Center “Kurchatov Institute”
Author for correspondence.
Email: zagos@inbox.ru
Russian Federation,
Moscow, 123182
T. E. Grigoriev
National Research Center “Kurchatov Institute”
Email: zagos@inbox.ru
Russian Federation,
Moscow, 123182
S. V. Krasheninnikov
National Research Center “Kurchatov Institute”
Email: zagos@inbox.ru
Russian Federation,
Moscow, 123182
E. V. Cuevda
Kuban State Medical University, Ministry of Healthof Russia
Email: zagos@inbox.ru
Russian Federation, Krasnodar, 350063
E. A. Gubareva
Kuban State Medical University, Ministry of Healthof Russia
Email: zagos@inbox.ru
Russian Federation, Krasnodar, 350063
A. V. Bakirov
National Research Center “Kurchatov Institute”; Enikolopov Institute of Synthetic Polymeric Materials, Russian Academy of Sciences
Email: zagos@inbox.ru
Russian Federation,
Moscow, 123182; Moscow, 117393
S. N. Chvalun
National Research Center “Kurchatov Institute”; Enikolopov Institute of Synthetic Polymeric Materials, Russian Academy of Sciences
Email: zagos@inbox.ru
Russian Federation,
Moscow, 123182; Moscow, 117393