Bone cements in the calcium phosphate–chitosan systems containing magnesium and zinc

Abstract

Based on studying the possibility of the introduction of physiologically important cations into a cementing system, technology of fabrication of highly deformable calcium phosphate cements has been developed for bone tissue reconstruction in medicine. It has been elucidated that the method of introduction of metal cations (magnesium, zinc) into the cementing system has an effect on the formation of the microstructure and properties. The in vitro degradation of composite cements in simulated body fluids has been studied. Results have been obtained for the development of cements with tailored properties, which can be varied in different ranges.