Email this article Physical Fatigue and Morphofunctional State of the Myocardium in Experimental Chronic Stress
- Authors: Kondashevskaya M.V.1, Chereshneva M.V.2, Downey H.F.3,4, Manukhina E.B.3,5,4, Kuzhel O.P.6, Lazuko S.S.6, Sarapultsev A.P.2,7, Lapshin M.S.3, Komelkova M.V.3, Tseylikman V.E.3, Chereshnev V.A.2,7
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Affiliations:
- Research Institute of Human Morphology
- Institute of Immunology and Physiology
- South Ural State University
- University of North Texas Health Science Center
- Institute of General Pathology and Pathophysiology
- Vitebsk State Medical University
- Yeltsin Federal University
- Issue: Vol 485, No 1 (2019)
- Pages: 30-32
- Section: Physiology
- URL: https://journals.rcsi.science/0012-4966/article/view/154442
- DOI: https://doi.org/10.1134/S0012496619020042
- ID: 154442
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Abstract
The relationship between the development of skeletal muscle fatigue of a specific type in male Wistar rats and morphofunctional alterations in the myocardium in the posttraumatic stress disorder (PTSD) model has been investigated for the first time. The aggravation of oxidative stress in the cardiomyocytes and the related transformation of the cell structural components and the depletion of energy reserves in PTSD has been identified as one of the main factors that accelerate the onset of musculoskeletal fatigue.
About the authors
M. V. Kondashevskaya
Research Institute of Human Morphology
Author for correspondence.
Email: marivladiko@mail.ru
Russian Federation, Moscow,
117418
M. V. Chereshneva
Institute of Immunology and Physiology
Email: marivladiko@mail.ru
Russian Federation, Yekaterinburg, 620039
H. F. Downey
South Ural State University; University of North Texas Health Science Center
Email: marivladiko@mail.ru
Russian Federation, Chelyabinsk, 454080; Fort Worth, 76107
E. B. Manukhina
South Ural State University; Institute of General Pathology and Pathophysiology; University of North Texas Health Science Center
Email: marivladiko@mail.ru
Russian Federation, Chelyabinsk, 454080; Moscow, 125315; Fort Worth, 76107
O. P. Kuzhel
Vitebsk State Medical University
Email: marivladiko@mail.ru
Belarus, Vitebsk, 210009
S. S. Lazuko
Vitebsk State Medical University
Email: marivladiko@mail.ru
Belarus, Vitebsk, 210009
A. P. Sarapultsev
Institute of Immunology and Physiology; Yeltsin Federal University
Email: marivladiko@mail.ru
Russian Federation, Yekaterinburg, 620039; Yekaterinburg, Ural, 620002
M. S. Lapshin
South Ural State University
Email: marivladiko@mail.ru
Russian Federation, Chelyabinsk, 454080
M. V. Komelkova
South Ural State University
Email: marivladiko@mail.ru
Russian Federation, Chelyabinsk, 454080
V. E. Tseylikman
South Ural State University
Email: marivladiko@mail.ru
Russian Federation, Chelyabinsk, 454080
V. A. Chereshnev
Institute of Immunology and Physiology; Yeltsin Federal University
Email: marivladiko@mail.ru
Russian Federation, Yekaterinburg, 620039; Yekaterinburg, Ural, 620002
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