Cortical Somatosensory Neurons in WAG/Rij Rats Transform Firing Evoked by Simulation of Posterior Thalamic Nucleus from Tonic to Phasic at Age of 6 Months
- 作者: Tsvetaeva D.1, Sitnikova E.1, Raevsky V.1
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隶属关系:
- Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences
- 期: 卷 168, 编号 1 (2019)
- 页面: 1-4
- 栏目: Physiology
- URL: https://journals.rcsi.science/0007-4888/article/view/242161
- DOI: https://doi.org/10.1007/s10517-019-04632-8
- ID: 242161
如何引用文章
详细
Functional peculiarities of paralemniscal subdivision of the thalamocortical system were examined in normal Wistar and in WAG/Rij rats genetically prone to absence epilepsy. In 6-7-month-old WAG/Rij characterized by developed epileptic activity, the response of cortical somatosensory neurons to single electrical stimulation of the posterior thalamic nucleus was phasic, whereas in normal Wistar rats, similar reaction was tonic. The study views this phasic response as neural equivalent of spike-wave discharges known as typical EEG symptom of absence epilepsy.
作者简介
D. Tsvetaeva
Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences
Email: vraevsky@mail.ru
俄罗斯联邦, Moscow
E. Sitnikova
Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences
Email: vraevsky@mail.ru
俄罗斯联邦, Moscow
V. Raevsky
Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences
编辑信件的主要联系方式.
Email: vraevsky@mail.ru
俄罗斯联邦, Moscow