Experimental Evaluation of the Properties of 3D Porous Bone Substitute Based on Calcium Phosphate on the Model of Monocortical Diaphysial Femur Defect in Rats
- 作者: Dubrov V.1, Klimashina E.2,3, Shcherbakov I.1, Shipunov G.1, Putlyaev V.2,3, Evdokimov P.2,3, Tikhonov A.2, Zyuzin D.1, Danilova N.1, Mal’kov P.1
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隶属关系:
- Faculty of Fundamental Medicine
- Faculty of Material Sciences
- Faculty of Chemistry, M. V. Lomonosov Moscow State University
- 期: 卷 167, 编号 3 (2019)
- 页面: 400-403
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/241751
- DOI: https://doi.org/10.1007/s10517-019-04536-7
- ID: 241751
如何引用文章
详细
A new alloplastic high-permeable material based on tricalcium phosphate with Kelvin architectonics created by stereolithographic 3D-printing was studied in vivo. A monocortical defect of the femur was modeled in rats and the material was implanted into the defect area. In 24 weeks, the animals were euthanized and histological examination of the defect area was performed. One femur fracture with fixator migration was recorded after implantation of the studied material and the reference chronOS synthetic material. The studied material demonstrated better osteoconductive properties then traditional osteoplastic material, which was seen from greater number of bone trabeculae and their area in the defect area.
作者简介
V. Dubrov
Faculty of Fundamental Medicine
编辑信件的主要联系方式.
Email: vduort@gmail.com
俄罗斯联邦, Moscow
E. Klimashina
Faculty of Material Sciences; Faculty of Chemistry, M. V. Lomonosov Moscow State University
Email: vduort@gmail.com
俄罗斯联邦, Moscow; Moscow
I. Shcherbakov
Faculty of Fundamental Medicine
Email: vduort@gmail.com
俄罗斯联邦, Moscow
G. Shipunov
Faculty of Fundamental Medicine
Email: vduort@gmail.com
俄罗斯联邦, Moscow
V. Putlyaev
Faculty of Material Sciences; Faculty of Chemistry, M. V. Lomonosov Moscow State University
Email: vduort@gmail.com
俄罗斯联邦, Moscow; Moscow
P. Evdokimov
Faculty of Material Sciences; Faculty of Chemistry, M. V. Lomonosov Moscow State University
Email: vduort@gmail.com
俄罗斯联邦, Moscow; Moscow
A. Tikhonov
Faculty of Material Sciences
Email: vduort@gmail.com
俄罗斯联邦, Moscow
D. Zyuzin
Faculty of Fundamental Medicine
Email: vduort@gmail.com
俄罗斯联邦, Moscow
N. Danilova
Faculty of Fundamental Medicine
Email: vduort@gmail.com
俄罗斯联邦, Moscow
P. Mal’kov
Faculty of Fundamental Medicine
Email: vduort@gmail.com
俄罗斯联邦, Moscow