Morphological Changes in the Thymus of Newborn Rats Exposed to Endocrine Disruptor Dichlorodiphenyltrichloroethane (DDT) during the Prenatal Period
- 作者: Yaglova N.1, Tsomartova E.2, Nazimova S.1, Obernikhin S.1, Mukhamedova S.2, Pashina N.2, Musaeva D.2
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隶属关系:
- Laboratory of Endocrine System Development, Research Institute of Human Morphology
- Department of Histology, Cytology, and Embryology, I. M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of the Russian Federation
- 期: 卷 167, 编号 2 (2019)
- 页面: 297-299
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/241662
- DOI: https://doi.org/10.1007/s10517-019-04513-0
- ID: 241662
如何引用文章
详细
The structure of the thymus in newborn rats exposed in utero to endocrine disruptor DDT was studied. We found that exposure to low doses of DDT during pregnancy does not disturb thymus formation in the offspring, but leads to changes in its structure than manifested as slower lobulation, wider epithelium-free areas in the cortex, and lower number of thymic corpuscles in the medulla. The results attest to sensitivity of the reticuloepithelial stroma of the thymus to the effects of endocrine disruptor.
作者简介
N. Yaglova
Laboratory of Endocrine System Development, Research Institute of Human Morphology
编辑信件的主要联系方式.
Email: yaglova@mail.ru
俄罗斯联邦, Moscow
E. Tsomartova
Department of Histology, Cytology, and Embryology, I. M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of the Russian Federation
Email: yaglova@mail.ru
俄罗斯联邦, Moscow
S. Nazimova
Laboratory of Endocrine System Development, Research Institute of Human Morphology
Email: yaglova@mail.ru
俄罗斯联邦, Moscow
S. Obernikhin
Laboratory of Endocrine System Development, Research Institute of Human Morphology
Email: yaglova@mail.ru
俄罗斯联邦, Moscow
S. Mukhamedova
Department of Histology, Cytology, and Embryology, I. M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of the Russian Federation
Email: yaglova@mail.ru
俄罗斯联邦, Moscow
N. Pashina
Department of Histology, Cytology, and Embryology, I. M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of the Russian Federation
Email: yaglova@mail.ru
俄罗斯联邦, Moscow
D. Musaeva
Department of Histology, Cytology, and Embryology, I. M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of the Russian Federation
Email: yaglova@mail.ru
俄罗斯联邦, Moscow
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