Experimental Study of the Effectiveness of Phenolic Antioxidants in Male Infertility Caused by Pathospermia
- 作者: Borovskaya T.1, Kamalova S.1, Krivova N.2, Zaeva O.2, Poluektova M.1, Vychuzhanina A.1, Grigor’eva V.1, Plotnikov M.1, Goldberg V.3
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隶属关系:
- E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
- Research Institute of Biology and Biophysics, National Research Tomsk State University
- Research Institute of Oncology, Tomsk National Research Medical Center, Russian Academy of Sciences
- 期: 卷 166, 编号 1 (2018)
- 页面: 7-10
- 栏目: General Pathology and Pathophysiology
- URL: https://journals.rcsi.science/0007-4888/article/view/240792
- DOI: https://doi.org/10.1007/s10517-018-4276-6
- ID: 240792
如何引用文章
详细
The effect of phenolic antioxidants (dihydroquercetin, p-tyrosol, dibornol) on the morphology, functions, and redox processes in the reproductive cells of male rats was studied on the model of experimental pathospermia. All antioxidants reduced the percentage of degenerative forms of spermatozoa. Dibornol was most effective. Dihydroquercetin and p-tyrosol did not increase the total number of spermatozoa and the percentage of their mobile forms. These indicators were improved only by dibornol. After administration of all test drugs, the antioxidant potential of spermatozoa increased and did not significantly differ from the baseline values.
作者简介
T. Borovskaya
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
编辑信件的主要联系方式.
Email: repropharm@yandex.ru
俄罗斯联邦, Tomsk
S. Kamalova
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: repropharm@yandex.ru
俄罗斯联邦, Tomsk
N. Krivova
Research Institute of Biology and Biophysics, National Research Tomsk State University
Email: repropharm@yandex.ru
俄罗斯联邦, Tomsk
O. Zaeva
Research Institute of Biology and Biophysics, National Research Tomsk State University
Email: repropharm@yandex.ru
俄罗斯联邦, Tomsk
M. Poluektova
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: repropharm@yandex.ru
俄罗斯联邦, Tomsk
A. Vychuzhanina
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: repropharm@yandex.ru
俄罗斯联邦, Tomsk
V. Grigor’eva
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: repropharm@yandex.ru
俄罗斯联邦, Tomsk
M. Plotnikov
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: repropharm@yandex.ru
俄罗斯联邦, Tomsk
V. Goldberg
Research Institute of Oncology, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: repropharm@yandex.ru
俄罗斯联邦, Tomsk