Survival of Mesenchymal Stem Cells in Different Methods of Nebulization


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We compared survival of bone marrow mesenchymal stem cells after compressor, ultrasound, and mesh nebulization of the cell suspension over 10 min. Viability of stromal cells was best preserved after compressor nebulization (72%). Cell survival after ultrasonic nebulization was significantly lower (20%). After mesh nebulization, no live cells were found. Thus, compressor nebulization is the most preferable method of the production of cell aerosol for their delivery to the lower respiratory tract.

作者简介

A. Aver’yanov

Research Institute of Pulmonology, Federal Biomedical Agency

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Email: averyanovav@mail.ru
俄罗斯联邦, Moscow

A. Konoplyannikov

National Medical Radiology Research Center, Ministry of Health of the Russian Federation

Email: averyanovav@mail.ru
俄罗斯联邦, Obninsk

N. Antonov

Research Institute of Pulmonology, Federal Biomedical Agency

Email: averyanovav@mail.ru
俄罗斯联邦, Moscow

G. Osipova

Research Institute of Pulmonology, Federal Biomedical Agency

Email: averyanovav@mail.ru
俄罗斯联邦, Moscow

O. Vasil’eva

Research Institute of Pulmonology, Federal Biomedical Agency

Email: averyanovav@mail.ru
俄罗斯联邦, Moscow

M. Sakharova

Research Institute of Pulmonology, Federal Biomedical Agency

Email: averyanovav@mail.ru
俄罗斯联邦, Moscow

A. Tatarskii

Research Institute of Pulmonology, Federal Biomedical Agency

Email: averyanovav@mail.ru
俄罗斯联邦, Moscow

V. Kobylyansky

Research Institute of Pulmonology, Federal Biomedical Agency

Email: averyanovav@mail.ru
俄罗斯联邦, Moscow


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