Regeneration Potential of Lymphoid Tissue of Small Intestine in Mice after Exposure to Low-Intensity Radiation
- 作者: Klochkova S.1, Kvaratskheliya A.2, Alekseeva N.2, Nikityuk D.3
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隶属关系:
- I. M. Sechenov First Medical State University
- N. N. Burdenko Voronezh State Medical University
- Federal Research Center of Nutrition, Biotechnology, and Food Safety
- 期: 卷 164, 编号 2 (2017)
- 页面: 214-217
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/239509
- DOI: https://doi.org/10.1007/s10517-017-3961-1
- ID: 239509
如何引用文章
详细
Number and size of aggregated lymphoid nodules in the small intestine of mice exposed to radiation using a γ-irradiation unit GOBO-60 with 137Cs source were measured using the methods of visual microscopy and morphometry. Morphological status of the nodules was estimated on days 4, 28, 60, and 90 after the exposure. Significant changes were observed in the lymphoid system of the small intestine after exposure to low-intensity radiation. The size of aggregated lymphoid nodules decreased and the relative number of cells with degenerative changes increased. Regenerative processes were observed as soon as on day 4 of the rehabilitation period. However, the number and sizes of aggregated lymphoid nodules (length, width, and section area), and the ratio of lymphoid nodules with germinal center were still lower than in the control. The number of cells forming lymphoid interstitial plaques was close to the control on days 28-90 of the rehabilitation process.
作者简介
S. Klochkova
I. M. Sechenov First Medical State University
Email: alexeevant@list.ru
俄罗斯联邦, Moscow
A. Kvaratskheliya
N. N. Burdenko Voronezh State Medical University
Email: alexeevant@list.ru
俄罗斯联邦, Voronezh
N. Alekseeva
N. N. Burdenko Voronezh State Medical University
编辑信件的主要联系方式.
Email: alexeevant@list.ru
俄罗斯联邦, Voronezh
D. Nikityuk
Federal Research Center of Nutrition, Biotechnology, and Food Safety
Email: alexeevant@list.ru
俄罗斯联邦, Moscow
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