Anterior Mediastinal Lymph Nodes in Chemically Induced Breast Cancer
- 作者: Kazakov O.1, Kabakov A.1, Poveshchenko A.1, Raiter T.1, Strunkin D.1, Ishchenko I.1, Lykov A.1, Michurina S.1, Konenkov V.1
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隶属关系:
- Research Institute of Experimental and Clinical Lymphology
- 期: 卷 164, 编号 2 (2017)
- 页面: 186-190
- 栏目: Oncology
- URL: https://journals.rcsi.science/0007-4888/article/view/239469
- DOI: https://doi.org/10.1007/s10517-017-3954-0
- ID: 239469
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详细
The anterior mediastinal lymph nodes were analyzed morphometrically in rats with chemically provoked breast cancer. Rats with untreated breast cancer and animals receiving chemotherapy demonstrated decreased volumes of paracortical region and lymphoid nodules with the germinal centers accompanied by extended medullary thymic substance. Resection of largest focus of breast tumor improved the filtration barrier potential of anterior mediastinal lymph nodes, up-regulated the proliferative activity of lymphoid cells in T-cell zones, and down-regulated proliferation of plasmatic cells.
作者简介
O. Kazakov
Research Institute of Experimental and Clinical Lymphology
编辑信件的主要联系方式.
Email: kazakoff_oleg@mail.ru
俄罗斯联邦, Novosibirsk
A. Kabakov
Research Institute of Experimental and Clinical Lymphology
Email: kazakoff_oleg@mail.ru
俄罗斯联邦, Novosibirsk
A. Poveshchenko
Research Institute of Experimental and Clinical Lymphology
Email: kazakoff_oleg@mail.ru
俄罗斯联邦, Novosibirsk
T. Raiter
Research Institute of Experimental and Clinical Lymphology
Email: kazakoff_oleg@mail.ru
俄罗斯联邦, Novosibirsk
D. Strunkin
Research Institute of Experimental and Clinical Lymphology
Email: kazakoff_oleg@mail.ru
俄罗斯联邦, Novosibirsk
I. Ishchenko
Research Institute of Experimental and Clinical Lymphology
Email: kazakoff_oleg@mail.ru
俄罗斯联邦, Novosibirsk
A. Lykov
Research Institute of Experimental and Clinical Lymphology
Email: kazakoff_oleg@mail.ru
俄罗斯联邦, Novosibirsk
S. Michurina
Research Institute of Experimental and Clinical Lymphology
Email: kazakoff_oleg@mail.ru
俄罗斯联邦, Novosibirsk
V. Konenkov
Research Institute of Experimental and Clinical Lymphology
Email: kazakoff_oleg@mail.ru
俄罗斯联邦, Novosibirsk