Pathogenetic Mechanisms of Outbreak and Development of Cardiac Autonomic Neuropathy in Patients with Metabolic Syndrome
- 作者: Kseneva S.1, Borodulina E.1, Trifonova O.1, Timofeev M.1, Udut V.1,2
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隶属关系:
- E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
- National Research Tomsk State University
- 期: 卷 164, 编号 1 (2017)
- 页面: 10-14
- 栏目: General Pathology and Pathophysiology
- URL: https://journals.rcsi.science/0007-4888/article/view/239321
- DOI: https://doi.org/10.1007/s10517-017-3914-8
- ID: 239321
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详细
A cross-sectional study of universe sample of patients (N=135; mean age —49.7±0.8 years) with metabolic syndrome yielded the incidence of cardiac autonomic neuropathy of 37.5%. The pathogenetic peculiarities were revealed for the onset and development of this neuropathy. At the early stages, the progress of cardiac autonomic neuropathy closely correlated with elevation of blood glucose, while endothelial dysfunction progressing at the later period against the background of persistent hyperglycemia is viewed as an extra factor contributing to the development of this disease.
作者简介
S. Kseneva
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
编辑信件的主要联系方式.
Email: viksbest@mail.ru
俄罗斯联邦, Tomsk
E. Borodulina
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: viksbest@mail.ru
俄罗斯联邦, Tomsk
O. Trifonova
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: viksbest@mail.ru
俄罗斯联邦, Tomsk
M. Timofeev
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: viksbest@mail.ru
俄罗斯联邦, Tomsk
V. Udut
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences; National Research Tomsk State University
Email: viksbest@mail.ru
俄罗斯联邦, Tomsk; Tomsk