Involvement of Microflora Metabolites in Up-Regulation of Electrical Activity in Rat Small Intestine
- 作者: Tropskaya N.1, Kislyakova E.1, Popova T.1
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隶属关系:
- N. V. Sklifosovsky Research Institute of Emergency Medicine, Moscow Department of Health
- 期: 卷 163, 编号 6 (2017)
- 页面: 796-800
- 栏目: Experimental Methods for Clinical Practice
- URL: https://journals.rcsi.science/0007-4888/article/view/239276
- DOI: https://doi.org/10.1007/s10517-017-3906-8
- ID: 239276
如何引用文章
详细
The study examined implication of tributyrin, a metabolic precursor in small intestinal microflora, in stimulation of electrical activity of duodenum and jejunum. Enteral administration of tributyrin enhanced electrical activity of both examined structures in small intestine with elimination of the rest periods. The stimulatory effect was manifested in a prolongation of the periods of irregular activity. The up-regulating effects of tributyrin on electrical activity in upper segments of small intestine are mediated via the cholecystokinin receptors being also associated with activation of cholinergic and blockade of nitrinergic signal transduction pathways.
作者简介
N. Tropskaya
N. V. Sklifosovsky Research Institute of Emergency Medicine, Moscow Department of Health
编辑信件的主要联系方式.
Email: ntropskaya@mail.ru
俄罗斯联邦, Moscow
E. Kislyakova
N. V. Sklifosovsky Research Institute of Emergency Medicine, Moscow Department of Health
Email: ntropskaya@mail.ru
俄罗斯联邦, Moscow
T. Popova
N. V. Sklifosovsky Research Institute of Emergency Medicine, Moscow Department of Health
Email: ntropskaya@mail.ru
俄罗斯联邦, Moscow