Peptides (Epigenetic Regulators) in the Structure of Rodents with a Long and Short Lifespan
- 作者: Khavinson V.1,2, Kormilets D.3, Mar’yanovich A.2
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隶属关系:
- St. Petersburg Institute of Bioregulation and Gerontology
- I. I. Mechnikov North-Western State Medical University
- S. M. Kirov Military Medical Academy
- 期: 卷 163, 编号 5 (2017)
- 页面: 671-676
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/239183
- DOI: https://doi.org/10.1007/s10517-017-3876-x
- ID: 239183
如何引用文章
详细
We have discovered motives of short-chain epigenetically active peptides in some proteins of long-lived African mole rat Heterocephalus glaber. These epigenetic regulators are located in the protein structure between lysine and arginine residues, thus facilitating their release in limited proteolysis. Some of these epigenetic regulators are not found in the proteins of short-lived species — Norway rat Rattus norvegicus and house mouse Mus musculus.
作者简介
V. Khavinson
St. Petersburg Institute of Bioregulation and Gerontology; I. I. Mechnikov North-Western State Medical University
Email: atm52@mail.ru
俄罗斯联邦, St. Petersburg; St. Petersburg
D. Kormilets
S. M. Kirov Military Medical Academy
Email: atm52@mail.ru
俄罗斯联邦, St. Petersburg
A. Mar’yanovich
I. I. Mechnikov North-Western State Medical University
编辑信件的主要联系方式.
Email: atm52@mail.ru
俄罗斯联邦, St. Petersburg