Free Immunoglobulin Light Chains as Criteria of Extracorporeal Hemocorrection in Patients with Monoclonal Gammopathies
- 作者: Lyubimova N.1, Timofeeva Y.1, Gromova E.1, Kuznetsova L.1, Votyakova O.1, Kushlinskii N.1
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隶属关系:
- N. N. Blokhin Russian Cancer Research Center, Ministry of Health of the Russian Federation
- 期: 卷 163, 编号 4 (2017)
- 页面: 493-496
- 栏目: Experimental Methods for Clinical Practice
- URL: https://journals.rcsi.science/0007-4888/article/view/239033
- DOI: https://doi.org/10.1007/s10517-017-3836-5
- ID: 239033
如何引用文章
详细
Elimination of free immunoglobulin light chains with the use of EMic2 selective filters was carried out in 12 patients with monoclonal gammopathies and high production of free immunoglobulin light chains. We showed that extracorporeal detoxification for direct removal of excessive free immunoglobulin light chains from the circulation is advisable for these patients, irrespective of the presence and severity of renal insufficiency. Rapid reduction or elimination of free light chains of immunoglobulins in the course of selective extracorporeal elimination helps to prevent the development of irreversible renal failure and to perform adequate antitumor therapy.
作者简介
N. Lyubimova
N. N. Blokhin Russian Cancer Research Center, Ministry of Health of the Russian Federation
Email: biochimia@yandex.ru
俄罗斯联邦, Moscow
Yu. Timofeeva
N. N. Blokhin Russian Cancer Research Center, Ministry of Health of the Russian Federation
Email: biochimia@yandex.ru
俄罗斯联邦, Moscow
E. Gromova
N. N. Blokhin Russian Cancer Research Center, Ministry of Health of the Russian Federation
Email: biochimia@yandex.ru
俄罗斯联邦, Moscow
L. Kuznetsova
N. N. Blokhin Russian Cancer Research Center, Ministry of Health of the Russian Federation
Email: biochimia@yandex.ru
俄罗斯联邦, Moscow
O. Votyakova
N. N. Blokhin Russian Cancer Research Center, Ministry of Health of the Russian Federation
Email: biochimia@yandex.ru
俄罗斯联邦, Moscow
N. Kushlinskii
N. N. Blokhin Russian Cancer Research Center, Ministry of Health of the Russian Federation
编辑信件的主要联系方式.
Email: biochimia@yandex.ru
俄罗斯联邦, Moscow