Adrenoceptors in Dopaminergic Regulation of Rat Myocardial Contractility in Rats During Ontogeny

G. A. Bilalova; F. G. Sitdikov; N. B. Dikopol’skaya; M. V. Shaikhelislamova; T. L. Zefirov

doi:10.1007/s10517-017-3709-y

Adrenoceptors in Dopaminergic Regulation of Rat Myocardial Contractility in Rats During Ontogeny

作者: Bilalova G.¹, Sitdikov F.¹, Dikopol’skaya N.¹, Shaikhelislamova M.¹, Zefirov T.¹
隶属关系:
1. Department of Human Health Protection, Kazan (Volga Region) Federal University
期: 卷 162, 编号 6 (2017)
页面: 769-772
栏目: Article
URL: https://journals.rcsi.science/0007-4888/article/view/238547
DOI: https://doi.org/10.1007/s10517-017-3709-y
ID: 238547

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The effects of different dopamine concentrations on contractility of myocardium with blocked α- or β-adrenoceptors were examined in vitro in 21- and 100-day old rats. In myocardial strips with blocked α-adrenoceptors, dopamine (10^—5 M) increased the right atrial contractile force. By contrast, this neurotransmitter (10^—9-10^—5 M) reduced the contractile force of atrial and ventricular strips with blocked β-adrenoceptors.