Effects of Melatonin on Differentiation Potential of Ito Cells in Mice with Induced Fibrosis of the Liver
- 作者: Nalobin D.1, Suprunenko E.1, Golichenkov V.1
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隶属关系:
- M. V. Lomonosov Moscow State University
- 期: 卷 161, 编号 6 (2016)
- 页面: 845-849
- 栏目: Morphology and Pathomorphology
- URL: https://journals.rcsi.science/0007-4888/article/view/237843
- DOI: https://doi.org/10.1007/s10517-016-3526-8
- ID: 237843
如何引用文章
详细
We studied the effects of melatonin on differentiation potential of Ito cells during atypical regeneration of mouse liver under conditions of CCl4-induced fibrosis. The dynamics of fibrosis was traced at the histological level and the effects of melatonin on the differentiation potential of mouse Ito cells were evaluated. Melatonin alleviated fibrotic changes in the liver tissue and reduced differentiation of Ito cells into myofibroblasts under conditions of atypical regeneration of the liver in induced fibrosis. The hepatoprotective role of melatonin was shown.
作者简介
D. Nalobin
M. V. Lomonosov Moscow State University
编辑信件的主要联系方式.
Email: denis.nalobin@gmail.com
俄罗斯联邦, Moscow
E. Suprunenko
M. V. Lomonosov Moscow State University
Email: denis.nalobin@gmail.com
俄罗斯联邦, Moscow
V. Golichenkov
M. V. Lomonosov Moscow State University
Email: denis.nalobin@gmail.com
俄罗斯联邦, Moscow