Functional State of the Heart during Spontaneous Nonconvulsive Seizure Activity at Various Times of the Day
- 作者: Mamalyga M.1, Mamalyga L.1
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隶属关系:
- Department for Anatomy and Physiology of Humans and Animals, Moscow Pedagogical State University
- 期: 卷 161, 编号 5 (2016)
- 页面: 629-633
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/237631
- DOI: https://doi.org/10.1007/s10517-016-3472-5
- ID: 237631
如何引用文章
详细
Circadian peculiarities of HR regulation and functional capacities of the heart in WAG/Rij rats with genetically determined absence epilepsy are related to spike-wave activity of the brain. The number of spike-wave discharges (SWD) is maximum at night, early morning, and evening time and decreases to minimum at 08.00-16.00. At night, functional capacities of the heart are reduced and stress test at night induces ischemic changes in the myocardium at a lower functional load than in the daytime (low level of SWD activity). The decrease in the number of SWD and spike-wave index during the daytime contributes to the central mechanisms of autonomic regulation of the heart. However, these capacities are reduced against the background of increased seizure activity during nighttime.
作者简介
M. Mamalyga
Department for Anatomy and Physiology of Humans and Animals, Moscow Pedagogical State University
编辑信件的主要联系方式.
Email: mamalyga_49@mail.ru
俄罗斯联邦, Moscow
L. Mamalyga
Department for Anatomy and Physiology of Humans and Animals, Moscow Pedagogical State University
Email: mamalyga_49@mail.ru
俄罗斯联邦, Moscow