Expression of Molecular Markers of Angiogenesis, Lymphangiogenesis, and Proliferation Depending on the Stage of Skin Melanoma
- 作者: Bgatova N.1, Lomakin A.2, Fursov S.2, Kachesov I.2, Chepko S.2, Isakova N.2, Borodin Y.1, Voytsitsky V.2, Konenkov V.1
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隶属关系:
- Institute of Clinical and Experimental Lymphology
- Novosibirsk Regional Clinical Oncological Center
- 期: 卷 161, 编号 4 (2016)
- 页面: 542-546
- 栏目: Oncology
- URL: https://journals.rcsi.science/0007-4888/article/view/237579
- DOI: https://doi.org/10.1007/s10517-016-3456-5
- ID: 237579
如何引用文章
详细
The expression of molecular markers characterizing activity of the tumor process and metastases (proliferation marker Ki-67, angiogenesis marker CD34, and lymphangiogenesis markers podoplanin and LYVE-1) was assessed by immunohictochemical method in the primary tumor specimens collected during surgery for cutaneous melanoma (40 patients). Proliferative activity of the tumor tissue and volume density of peritumoral blood and lymph vessels increased with increasing tumor malignancy, which could indicate the risk of metastases.
作者简介
N. Bgatova
Institute of Clinical and Experimental Lymphology
编辑信件的主要联系方式.
Email: n_bgatova@ngs.ru
俄罗斯联邦, Novosibirsk
A. Lomakin
Novosibirsk Regional Clinical Oncological Center
Email: n_bgatova@ngs.ru
俄罗斯联邦, Novosibirsk
S. Fursov
Novosibirsk Regional Clinical Oncological Center
Email: n_bgatova@ngs.ru
俄罗斯联邦, Novosibirsk
I. Kachesov
Novosibirsk Regional Clinical Oncological Center
Email: n_bgatova@ngs.ru
俄罗斯联邦, Novosibirsk
S. Chepko
Novosibirsk Regional Clinical Oncological Center
Email: n_bgatova@ngs.ru
俄罗斯联邦, Novosibirsk
N. Isakova
Novosibirsk Regional Clinical Oncological Center
Email: n_bgatova@ngs.ru
俄罗斯联邦, Novosibirsk
Yu. Borodin
Institute of Clinical and Experimental Lymphology
Email: n_bgatova@ngs.ru
俄罗斯联邦, Novosibirsk
V. Voytsitsky
Novosibirsk Regional Clinical Oncological Center
Email: n_bgatova@ngs.ru
俄罗斯联邦, Novosibirsk
V. Konenkov
Institute of Clinical and Experimental Lymphology
Email: n_bgatova@ngs.ru
俄罗斯联邦, Novosibirsk
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