Evidence of Echocardiography Validity in Model Experiments on Small Animals
- 作者: Kryzhanovskii S.1, Kolik L.1, Tsorin I.1, Ionova E.1, Stolyaruk V.1, Sorokina A.1, Vititnova M.1, Miroshkina I.1
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隶属关系:
- V. V. Zakusov Research Institute of Pharmacology
- 期: 卷 161, 编号 3 (2016)
- 页面: 434-438
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/237491
- DOI: https://doi.org/10.1007/s10517-016-3432-0
- ID: 237491
如何引用文章
详细
Dynamic echocardiographic monitoring in rats subjected to forced alcoholization showed the formation of disorders in intracardiac hemodynamics characteristic of ethanol cardiomyopathy formed by the end of 24-week continuous ethanol consumption. The results of echocardiographic monitoring were confirmed by histological and morphometric studies demonstrating fatty infiltration of the myocardium pathognomonic for this condition and bifocal dilatation of cardiac ventricles. These results persuasively demonstrate that echocardiographic studies on small animals are valid and can be used for search for cardiotropic drugs and studies of the mechanisms of their activities.
作者简介
S. Kryzhanovskii
V. V. Zakusov Research Institute of Pharmacology
编辑信件的主要联系方式.
Email: SAK-538@yandex.ru
俄罗斯联邦, Moscow
L. Kolik
V. V. Zakusov Research Institute of Pharmacology
Email: SAK-538@yandex.ru
俄罗斯联邦, Moscow
I. Tsorin
V. V. Zakusov Research Institute of Pharmacology
Email: SAK-538@yandex.ru
俄罗斯联邦, Moscow
E. Ionova
V. V. Zakusov Research Institute of Pharmacology
Email: SAK-538@yandex.ru
俄罗斯联邦, Moscow
V. Stolyaruk
V. V. Zakusov Research Institute of Pharmacology
Email: SAK-538@yandex.ru
俄罗斯联邦, Moscow
A. Sorokina
V. V. Zakusov Research Institute of Pharmacology
Email: SAK-538@yandex.ru
俄罗斯联邦, Moscow
M. Vititnova
V. V. Zakusov Research Institute of Pharmacology
Email: SAK-538@yandex.ru
俄罗斯联邦, Moscow
I. Miroshkina
V. V. Zakusov Research Institute of Pharmacology
Email: SAK-538@yandex.ru
俄罗斯联邦, Moscow
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