Effect of Audiogenic Seizures on the Dynamics of Fatty Acid Composition of Hippocampal Dental Gyrus in Krushinsky-Molodkina Rats
- 作者: Kulagina T.1, Aripovsky A.2, Savina T.3, Godukhin O.3
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隶属关系:
- Institute of Cell Biophysics, Russian Academy of Sciences
- State Research Center of Applied Microbiology and Biotechnology
- Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences
- 期: 卷 161, 编号 2 (2016)
- 页面: 241-244
- 栏目: Biophysics and Biochemistry
- URL: https://journals.rcsi.science/0007-4888/article/view/237300
- DOI: https://doi.org/10.1007/s10517-016-3386-2
- ID: 237300
如何引用文章
详细
Changes in the fatty acid composition of the hippocampal dentate gyrus in Krushinsky–Molodkina rats with hereditary predisposition to audiogenic seizures were studied in 1, 3, and 14 days after 1 or 5 seizures. Seizure activity changed the content of saturated and monounsaturated as well as polyunsaturated fatty acids at different terms after seizures. After seizures, the content of individual fatty acids changed in different directions. Similar shifts after 1 and 5 seizures were observed only for eicosapentaenoic acid at all observation terms. More pronounced changes in fatty acid composition were observed after 5 seizures. These results can be useful for the development of new approaches to correction of seizure activity.
作者简介
T. Kulagina
Institute of Cell Biophysics, Russian Academy of Sciences
编辑信件的主要联系方式.
Email: tpkulagina@rambler.ru
俄罗斯联邦, Pushchino
A. Aripovsky
State Research Center of Applied Microbiology and Biotechnology
Email: tpkulagina@rambler.ru
俄罗斯联邦, Obolensk
T. Savina
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences
Email: tpkulagina@rambler.ru
俄罗斯联邦, Pushchino
O. Godukhin
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences
Email: tpkulagina@rambler.ru
俄罗斯联邦, Pushchino
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